切换至 "中华医学电子期刊资源库"

中华消化病与影像杂志(电子版) ›› 2017, Vol. 07 ›› Issue (03) : 97 -100. doi: 10.3877/cma.j.issn.2095-2015.2017.03.001

所属专题: 文献

述评

炎症性肠病肠外表现的诊治策略
葛文松1,()   
  1. 1. 200092 上海交通大学医学院附属新华医院消化内科
  • 收稿日期:2017-04-07 出版日期:2017-06-01
  • 通信作者: 葛文松
  • 基金资助:
    国家自然科学基金(81200279)

Extraintestinal manifestations of inflammatory bowel disease: diagnosis and treatment

Wensong Ge1,()   

  1. 1. Department of Gastroenterology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School Medicine, Shanghai 200092, China
  • Received:2017-04-07 Published:2017-06-01
  • Corresponding author: Wensong Ge
  • About author:
    Corresponding author: Ge Wensong, Email:
引用本文:

葛文松. 炎症性肠病肠外表现的诊治策略[J/OL]. 中华消化病与影像杂志(电子版), 2017, 07(03): 97-100.

Wensong Ge. Extraintestinal manifestations of inflammatory bowel disease: diagnosis and treatment[J/OL]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2017, 07(03): 97-100.

炎症性肠病(inflammatory bowel disease,IBD)是一组病因不明的慢性非特异性肠道炎症性疾病,包括Crohn病(Crohn′s disease,CD)和溃疡性结肠炎(ulcerative colitis,UC),其临床表现多样,不仅累及肠道,亦可出现多种肠外表现(extraintestinal manifestations,EIMs),易造成误诊误治,及时诊断及合理治疗能够改善患者的病情和生活质量,本文就IBD常见EIMs的诊断和治疗策略进行探讨。

Objective

Inflammatory bowel disease(IBD)is a chronic and non-specific inflammatory disease with unknown etiology, which comprises Crohn disease(CD)and ulcerative colitis(UC). The clinical manifestations of IBD are variable.It predominantly affects the intestinal system, but it is associated with a large number of extraintestinal manifestations(EIMs), and this may lead to misdiagnosis or mistreatment.Timely diagnosis and reasonable treatment can improve the patient′s condition and the quality of life.In this paper, the diagnostic and treatment strategies about EIMs of IBD are discussed.

1
Ott C, Scholmerich J. Extraintestinal manifestations and complications in IBD[J]. Nat Rev Gastroenterol Hepatol, 2013, 10(10): 585-595.
2
Orchard TR, Wordsworth BP, Jewell DP.Peripheral arthropathies in inflammatory bowel disease: their articular distribution and natural history[J]. Gut, 1998, 42(3): 387-391.
3
Salvarani C, Vlachonikolis IG, van der Heijde DM, et al.Musculoskeletal manifestations in a population-based cohort of inflammatory bowel disease patients[J]. Scand J Gastroenterol, 2001, 36(12): 1307-1313.
4
Peeters H, Vander Cruyssen B, Mielants H, et al.Clinical and genetic factors associated with sacroiliitis in Crohn′s disease[J]. J Gastroenterol Hepatol, 2008, 23(1): 132-137.
5
Puhakka KB, Jurik AG, Schi?ttz-Christensen B, et al.MRI abnormalities of sacroiliac joints in early spondylarthropathy: a 1-year follow-up study[J]. Scand J Rheumatol, 2004, 33(5): 332-338.
6
Peluso R, Manguso F, Vitiello M, et al.Management of arthropathy in inflammatory bowel diseases[J]. Ther Adv Chronic Dis, 2015, 6(2): 65-77.
7
Braun J, Baraliakos X, Listing J, et al.Persistent clinical efficacy and safety of anti-tumour necrosis factor alpha therapy with infliximab in patients with ankylosing spondylitis over 5 years: evidence for different types of response[J]. Ann Rheumat Dis, 2008, 67(3): 340-345.
8
Requena L, Sanchez Yus E. Erythema nodosum[J]. Semin Cutan Med Surg, 2007, 26(2): 114-125.
9
Andrisani G, Guidi L, Papa A, et al.Anti-TNF alpha therapy in the management of extraintestinal manifestation of inflammatory bowel disease[J]. Eur Rev Med Pharmacol Sci, 2012, 16(7): 890-901.
10
Ruocco E, Sangiuliano S, Gravina AG, et al.Pyoderma gangrenosum: an updated review[J]. J Eur Acad Dermatol Venereol, 2009, 23(9): 1008-1017.
11
Lakatos PL, Lakatos L, Kiss LS, et al.Treatment of extraintestinal manifestations in inflammatory bowel disease[J]. Digestion, 2012, 86 Suppl 1: 28-35.
12
Ljung T, Staun M, Grove O, et al.Pyoderma gangrenosum associated with crohn disease: effect of TNF-alpha blockade with infliximab[J]. Scand J Gastroenterol, 2002, 37(9): 1108-1110.
13
Reinshagen M. Osteoporosis in inflammatory bowel disease[J]. J Crohns Colitis, 2008, 2(3): 202-207.
14
Bischoff-Ferrari HA, Willett WC, Wong JB, et al.Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials[J]. JAMA, 2005, 293(18): 2257-2264.
15
Soo I, Siffledeen J, Siminoski K, et al.Risedronate improves bone mineral density in Crohn′s disease: a two year randomized controlled clinical trial[J]. J Crohns Colitis, 2012, 6(7): 777-786.
16
Eaton JE, Talwalkar JA, Lazaridis KN, et al.Pathogenesis of primary sclerosing cholangitis and advances in diagnosis and management[J]. Gastroenterology, 2013, 145(3): 521-536.
17
Braden B, Halliday J, Aryasingha S, et al.Risk for colorectal neoplasia in patients with colonic Crohn′s disease and concomitant primary sclerosing cholangitis[J]. Clin Gastroenterol Hepatol, 2012, 10(3): 303-308.
18
Lindor KD, Kowdley KV, Luketic VA, et al.High-dose ursodeoxycholic acid for the treatment of primary sclerosing cholangitis[J]. Hepatology, 2009, 50(3): 808-814.
19
Higgins PD, Skup M, Mulani PM, et al.Increased risk of venous thromboembolic events with corticosteroid vs biologic therapy for inflammatory bowel disease[J]. Clin Gastroenterol Hepatol, 2015, 13(2): 316-321.
20
Chong LY, Fenu E, Stansby G, et al.Management of venous thromboembolic diseases and the role of thrombophilia testing: summary of NICE guidance[J]. BMJ, 2012, 344: e3979.
[1] 王亚红, 蔡胜, 葛志通, 杨筱, 李建初. 颅骨骨膜窦的超声表现一例[J/OL]. 中华医学超声杂志(电子版), 2024, 21(11): 1089-1091.
[2] 史学兵, 谢迎东, 谢霓, 徐超丽, 杨斌, 孙帼. 声辐射力弹性成像对不可切除肝细胞癌门静脉癌栓患者放射治疗效果的评价[J/OL]. 中华医学超声杂志(电子版), 2024, 21(08): 778-784.
[3] 李华志, 曹广, 刘殿刚, 张雅静. 不同入路下行肝切除术治疗原发性肝细胞癌的临床对比[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 52-55.
[4] 陈浩, 王萌. 胃印戒细胞癌的临床病理特征及治疗选择的研究进展[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 108-111.
[5] 刘柏隆, 周祥福. 压力性尿失禁阶梯治疗的项目介绍[J/OL]. 中华腔镜泌尿外科杂志(电子版), 2025, 19(01): 125-125.
[6] 刘柏隆. 女性压力性尿失禁阶梯治疗之手术治疗方案选择[J/OL]. 中华腔镜泌尿外科杂志(电子版), 2025, 19(01): 126-126.
[7] 李浩, 陈棋帅, 费发珠, 张宁伟, 李元东, 王硕晨, 任宾. 慢性肝病肝纤维化无创诊断的研究进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(09): 863-867.
[8] 谭瑞义. 小细胞骨肉瘤诊断及治疗研究现状与进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(08): 781-784.
[9] 崔军威, 蔡华丽, 胡艺冰, 胡慧. 亚甲蓝联合金属定位夹及定位钩针标记在乳腺癌辅助化疗后评估腋窝转移淋巴结的临床应用价值探究[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 625-632.
[10] 王誉英, 刘世伟, 王睿, 曾娅玲, 涂禧慧, 张蒲蓉. 老年乳腺癌新辅助治疗病理完全缓解的预测因素分析[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 641-646.
[11] 王子阳, 王宏宾, 刘晓旌. 血清标志物对甲胎蛋白阴性肝细胞癌诊断的研究进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 677-681.
[12] 陈慧, 邹祖鹏, 周田田, 张艺丹, 张海萍. 皮肤镜对头皮红斑性皮肤病辅助鉴别诊断的研究进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 692-698.
[13] 张平骥, 徐钰, 李天水, 庞文翼, 符师宁, 张梦圆. 重症患者镇静治疗现状及期望的调查研究[J/OL]. 中华临床医师杂志(电子版), 2024, 18(06): 562-567.
[14] 胡云鹤, 周玉焯, 付瑞瑛, 于凡, 李爱东. CHS-DRG付费制度下GB1分组住院费用影响因素分析与管理策略探讨[J/OL]. 中华临床医师杂志(电子版), 2024, 18(06): 568-574.
[15] 王昌前, 林婷婷, 宁雨露, 王颖杰, 谭文勇. 光免疫治疗在肿瘤领域的临床应用新进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(06): 575-583.
阅读次数
全文


摘要


AI


AI小编
你好!我是《中华医学电子期刊资源库》AI小编,有什么可以帮您的吗?