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中华消化病与影像杂志(电子版) ›› 2018, Vol. 08 ›› Issue (05) : 228 -231. doi: 10.3877/cma.j.issn.2095-2015.2018.05.009

所属专题: 文献

综述

门静脉高压性胃肠病的诊治进展
王明辉1, 李文波1, 刘晓峰1,()   
  1. 1. 250031 济南军区总医院消化科
  • 收稿日期:2018-04-26 出版日期:2018-10-01
  • 通信作者: 刘晓峰

Research advances in diagnosis and treatment of portal hypertensive gastroenteropathy

Minghui Wang1, Wenbo Li1, Xiaofeng Liu1,()   

  1. 1. Department of Gastroenterology and Hepatology, General Hospital of Jinan Military Command Region, Jinan 250031, China
  • Received:2018-04-26 Published:2018-10-01
  • Corresponding author: Xiaofeng Liu
  • About author:
    Corresponding author: Liu Xiaofeng, Email:
引用本文:

王明辉, 李文波, 刘晓峰. 门静脉高压性胃肠病的诊治进展[J]. 中华消化病与影像杂志(电子版), 2018, 08(05): 228-231.

Minghui Wang, Wenbo Li, Xiaofeng Liu. Research advances in diagnosis and treatment of portal hypertensive gastroenteropathy[J]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2018, 08(05): 228-231.

门静脉高压性胃病和肠病通常指继发于门静脉高压的胃肠道黏膜病变,可导致消化道出血。其发病机制不明,可能与血流动力学改变及其分子机制有关,药物治疗、内镜治疗、手术治疗是主要的治疗手段。本文就门静脉高压性胃肠病的发病机制、内镜表现、治疗方案等方面进行文献回顾,以期为临床诊治提供参考。

Portal hypertensive gastroenteropathy usually refer to gastrointestinal mucosal lesions secondary to portal hypertension, which can lead to gastrointestinal bleeding.The pathogenesis is unknown, and it may be related to the hemodynamic changes and its molecular mechanism.Drug therapy, endoscopic treatment and surgery are the main treatment methods.This article reviews the current research advances in pathogenesis, endoscopic manifestation and treatment of portal hypertensive gastroenteropathy in order to provide reference for clinical practice.

1
王帅,祁小龙.门静脉高压的分类及诊断思路[J].实用肝脏病杂志,2018,21(1): 14-17.
2
Palmer ED.Erosive gastritis in cirrhosis;influence of portal hypertension on the gastric mucosa[J]. Am J Dig Dis, 1957, 2(1): 31-36.
3
Sarfeh IJ, Tarnawski A. Portal hypertensive gastritis[J]. Gastroenterology, 1984, 86(3): 592.
4
Mccormack TT, Sims J, Eyre-Brook I, et al.Gastric lesions in portal hypertension: inflammatory gastritis or congestive gastropathy?[J]. Gut, 1985, 26(11): 1226-1232.
5
Gjeorgjievski M, Cappell MS.Portal hypertensive gastropathy: A systematic review of the pathophysiology, clinical presentation, natural history and therapy[J]. World J Hepatol, 2016, 8(4): 231-262.
6
Casas M, Vergara M, Brullet E, et al.Inter and intra-observer concordance for the diagnosis of portal hypertension gastropathy[J]. Rev Esp Enferm Dig, 2018, 110(3): 166-171.
7
李子银.非选择性β受体阻滞剂对门静脉高压性胃病治疗效果的临床观察[D].济南:山东大学,2014.
8
陈世耀,林秋燕,黄晓铨.门静脉高压性胃病的诊断及发病机制研究[J].诊断学理论与实践,2016(05): 451-454.
9
吕暘,陈豪,黄岩,等.肝硬化门静脉高压性胃病进展的临床相关因素分析[J].同济大学学报(医学版),2018(1): 114-117.
10
Tan S, Chen X, Xu M, et al.PGE2 /EP4 receptor attenuated mucosal injury via beta-arrestin1/Src/EGFR-mediated proliferation in portal hypertensive gastropathy[J]. Br J Pharmacol, 2017, 174(9): 848-866.
11
Urrunaga NH, Rockey DC.Portal hypertensive gastropathy and colopathy[J]. Clin Liver Dis, 2014, 18(2): 389-406.
12
Kalafateli M, Triantos CK, Nikolopoulou V, et al.Non-variceal gastrointestinal bleeding in patients with liver cirrhosis: a review[J]. Dig Dis Sci, 2012, 57(11): 2743-2754.
13
王虹.肝硬化门静脉高压性胃病的分类和诊断认识[J].诊断学理论与实践,2016(05): 446-450.
14
Ma C, Chen CH, Liu TC.The spectrum of gastric pathology in portal hypertension-An endoscopic and pathologic study of 550 cases[J]. Pathol Res Pract, 2016, 212(8): 704-709.
15
Reiberger T, Puspok A, Schoder M, et al.Austrian consensus guidelines on the management and treatment of portal hypertension(Billroth III)[J]. Wien Klin Wochenschr, 2017, 129(Suppl 3): 135-158.
16
Patwardhan VR, Cardenas A. Review article: the management of portal hypertensive gastropathy and gastric antral vascular ectasia in cirrhosis[J]. Aliment Pharmacol Ther, 2014, 40(4): 354-362.
17
Perez-Ayuso RM, Pique JM, Bosch J, et al.Propranolol in prevention of recurrent bleeding from severe portal hypertensive gastropathy in cirrhosis[J]. Lancet, 1991, 337(8755): 1431-1434.
18
Gjeorgjievski M, Cappell MS.Portal hypertensive gastropathy: A systematic review of the pathophysiology, clinical presentation, natural history and therapy[J]. World J Hepatol, 2016, 8(4): 231-262.
19
Hanafy AS, El HA.Efficacy of argon plasma coagulation in the management of portal hypertensive gastropathy[J]. Endosc Int Open, 2016, 4(10): E1057-E1062.
20
Jain S, Kalla M, Suleman A, et al.Proximal spleno-renal shunt with retro-aortic left renal vein in a patient with extra-hepatic portal vein obstruction: first case report[J]. BMC Surg, 2017, 17(1): 65.
21
Buechter M, Kahraman A, Manka P, et al.Partial spleen embolization reduces the risk of portal hypertension-induced upper gastrointestinal bleeding in patients not eligible for TIPS implantation[J]. PLoS One, 2017, 12(5): e177401.
22
Kozarek RA, Botoman VA, Bredfeldt JE, et al.Portal colopathy: prospective study of colonoscopy in patients with portal hypertension[J]. Gastroenterology, 1991, 101(5): 1192-1197.
23
Jeon SR, Kim JO.Capsule Endoscopy for Portal Hypertensive Enteropathy[J]. Gastroenterol Res Pract, 2016, 2016: 8501394.
24
Chandrasekar TS, Janakan GB, Chandrasekar VT, et al.Spectrum of small-bowel mucosal abnormalities identified by capsule endoscopy in patients with portal hypertension of varied etiology[J]. Indian J Gastroenterol, 2017, 36(1): 32-37.
25
Aller M A, Arias J L, Cruz A, et al.Inflammation: a way to understanding the evolution of portal hypertension[J]. Theor Biol Med Model, 2007, 4: 44.
26
伍学艳,张培建.门静脉高压性结肠病发生机制及防治进展[J].中国现代普通外科进展,2010,13(8): 648-651.
27
Ganguly S, Sarin SK, Bhatia V, et al.The prevalence and spectrum of colonic lesions in patients with cirrhotic and noncirrhotic portal hypertension[J]. Hepatology, 1995, 21(5): 1226-1231.
28
De Palma GD, Rega M, Masone S, et al.Mucosal abnormalities of the small bowel in patients with cirrhosis and portal hypertension: a capsule endoscopy study[J]. Gastrointest Endosc, 2005, 62(4): 529-534.
29
Tsai CJ, Sanaka MR, Menon KV, et al.Balloon-assisted enteroscopy in portal hypertensive enteropathy[J]. Hepatogastroenterology, 2014, 61(134): 1635-1641.
30
Yamakado S, Kanazawa H, Kobayashi M. Portal hypertensive colopathy: endoscopic findings and the relation to portal pressure[J]. Intern Med, 1995, 34(3): 153-157.
31
Tang SJ.Portal hypertensive polypoid enteropathy[J]. Gastrointest Endosc, 2011, 73(6): 1332.
32
Bini EJ, Lascarides CE, Micale PL, et al.Mucosal abnormalities of the colon in patients with portal hypertension: an endoscopic study[J]. Gastrointest Endosc, 2000, 52(4): 511-516.
33
Aydede H, Sakarya A, Erhan Y, et al.Effects of octreotide and propranolol on colonic mucosa in rats with portal hypertensive colopathy[J]. Hepatogastroenterology, 2003, 50(53): 1352-1355.
34
Branco JC, Carvalho R, Alberto SF, et al.Long-acting octreotide is effective in the treatment of portal hypertensive colopathy[J]. Gastroenterol Hepatol, 2017, 40(8): 536-537.
35
胡美迪,郭贵海.门静脉高压性肠病的研究现状[J].世界华人消化杂志,2009,17(20): 2054-2057.
36
Shiraishi M, Hiroyasu S, Higa T, et al.Successful management of ruptured duodenal varices by means of endoscopic variceal ligation: report of a case[J]. Gastrointest Endosc, 1999, 49(2): 255-257.
37
Sato T, Akaike J, Toyota J, et al.Clinicopathological features and treatment of ectopic varices with portal hypertension[J]. Int J Hepatol, 2011, 2011: 960720.
38
Boyer TD, Haskal ZJ.The Role of Transjugular Intrahepatic Portosystemic Shunt(TIPS)in the Management of Portal Hypertension: update 2009[J]. Hepatology, 2010, 51(1): 306.
39
Tokodai K, Kawagishi N, Miyagi S, et al.Splenectomy for Severe Intestinal Bleeding Caused by Portal Hypertensive Enteropathy After Pediatric Living-Donor Liver Transplantation: A Report of Three Cases[J]. Transplant Proc, 2017, 49(5): 1129-1132.
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