探究超声剪切波弹性成像（SWE）在直肠癌诊断及淋巴结转移评估中的应用价值。

回顾性选取徐州市第一人民医院2021年10月至2024年10月收治的96例直肠肿瘤患者为研究对象，通过病理检查结果对照分析SWE对直肠癌的诊断价值，多因素Logistic回归分析SWE参数与淋巴结转移关系，绘制ROC曲线分析SWE参数对淋巴结转移的评估价值。

96例直肠肿瘤患者病理检查结果显示，直肠癌患者75例，非直肠癌患者21例。SWE检查显示，直肠癌患者杨氏模量均值、弹性方差均高于非直肠癌患者（P<0.05），直肠癌患者与非直肠癌患者弹性对比度比较差异无统计学意义（P>0.05）。ROC曲线分析显示，单一指标诊断直肠癌时，杨氏模量值均值诊断直肠癌的AUC为0.850，敏感度73.33%，特异度为90.48%，弹性方差诊断直肠癌的AUC为0.846，敏感度为62.67%，特异度为95.24%，联合诊断时，杨氏模量均值、弹性方差联合诊断直肠癌的AUC最高为0.946，敏感度为95.67%，特异度为90.48%。75例直肠癌患者经根治性手术明确淋巴结转移31例，淋巴结转移患者杨氏模量均值、弹性方差均高于淋巴结未转移患者（P<0.05），淋巴结转移与淋巴结未转移患者弹性对比度比较差异无统计学意义（P>0.05）。ROC曲线分析显示，单一指标评估直肠癌淋巴结转移时，杨氏模量值均值评估淋巴结转移的AUC为0.828，敏感度67.14%，特异度为88.64%，弹性方差评估淋巴结转移AUC为0.848，敏感度为74.19%，特异度为81.28%，联合诊断时，杨氏模量均值、弹性方差联合评估淋巴结转移为AUC最高为0.927，敏感度为96.77%，特异度为88.64%。

SWE参数杨氏模量均值、弹性方差在直肠癌诊断及淋巴结转移评估中具有重要价值。

To investigate the application value of ultrasound shear wave elastography (SWE) in the diagnosis of rectal cancer and evaluation of lymph node metastasis.

A total of 96 patients with rectal tumors admitted to Xuzhou First People's Hospital from October 2021 to October 2024 were selected as the research subjects. The value of SWE in the diagnosis of rectal cancer and evaluation of lymph node metastasis was analyzed.

Pathological results showed that among 96 patients with rectal tumors enrolled in this study, there were 75 patients with rectal cancer and 21 patients without. The mean Young's modulus and elastic variance of patients with rectal cancer were higher than those of patients without (P<0.05). There was no significant difference in elasticity contrast between patients with rectal cancer and those without (P>0.05). ROC curve analysis showed that for diagnosing rectal cancer, the AUC, specificity and sensitivity of mean Young's modulus were 0.850, 73.33% and 90.48%. The AUC, specificity and sensitivity of elastic variance were 0.846, 62.67% and 95.24%. The AUC, specificity and sensitivity of combination of mean Young's modulus and elastic variance were 0.946, 95.67% and 90.48%. Among 75 patients with rectal cancer, 31 patients were confirmed to have lymph node metastasis after radical surgery. The mean Young's modulus and elastic variance of patients with lymph node metastasis were higher than those of patients without (P<0.05). There was no significant difference in elasticity contrast between patients with lymph node metastasis and those without (P>0.05). ROC curve analysis showed that for evaluating lymph node metastasis, the AUC, specificity and sensitivity of mean Young's modulus were 0.828, 67.14% and 88.64%. The AUC, specificity and sensitivity of elastic variance were 0.848, 74.19% and 81.28%. The AUC, specificity and sensitivity of combination of mean Young's modulus and elastic variance were 0.927, 96.77% and 88.64%.

The SWE parameters (mean Young's modulus and elastic variance) are of high value in the diagnosis of rectal cancer and evaluation of lymph node metastasis.