探讨胃充盈超声在评估3~12岁功能性消化不良（FD）患儿治疗前后胃排空功能变化中的临床应用价值。

本研究为回顾性观察性研究，选取延安市人民医院2023年7月至2025年7月收治的150例FD患儿作为研究对象，均给予复方乳酶生片口服治疗，3~6岁患儿每次1片、7~12岁患儿每次2片，每日3次，连续治疗14 d。采用胃充盈超声分别于治疗前后测定胃排空50%时间（GET50）、胃排空率、胃窦收缩频率及胃壁厚度，检测胃动素、胃泌素、5-羟色胺水平，记录临床症状评分（包括餐后饱胀、早饱、上腹痛及腹胀）。

治疗后，患儿餐后饱胀、早饱、上腹痛、腹胀症状评分显著降低，GET50、2 h残余率及胃窦收缩指数明显下降，胃排空率及胃收缩频率显著升高，血清胃动素、胃泌素、5-羟色胺水平显著升高，胃壁厚度较治疗前明显缩小（P<0.05）。

胃充盈超声能准确反映FD患儿治疗前后胃排空功能及胃壁厚度的变化，其结果与症状及胃动力指标改善一致。

To explore the clinical application value of gastric filling ultrasonography in evaluating the changes in gastric emptying function in children aged 3-12 years with functional dyspepsia (FD) before and after treatment.

This study was a retrospective observational study. A total of 150 children with FD admitted to Yan'an People's Hospital from July 2023 to July 2025 were selected as the research objects. They were given compound lactasin tablets orally. Children aged 3-6 years old took one tablet each time, and children aged 7-12 years old took two tablets each time, three times a day for 14 days. Gastric emptying 50% time (GET50), gastric emptying rate, antral contraction frequency and gastric wall thickness were measured by gastric filling ultrasound before and after treatment, and the levels of motilin, gastrin and 5-hydroxytryptamine were detected. Meanwhile, the clinical symptom scores (postprandial fullness, early satiety, epigastric pain, abdominal distension) were recorded.

After treatment, the symptom scores of postprandial fullness, early satiety, epigastric pain, and abdominal distension were significantly reduced, the GET50, 2h residual rate, and antral contraction index were significantly decreased, while the gastric emptying rate and gastric contraction frequency were significantly increased, the serum levels of motilin, gastrin, and 5-hydroxytryptamine were significantly increased, and gastric wall thickness was significantly reduced compared with that before treatment (P<0.05).

Gastric filling ultrasound can accurately reflect the changes of gastric emptying function and gastric wall thickness in children with FD before and after treatment, and its results are consistent with the improvement of symptoms and gastric motility indicators.