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中华消化病与影像杂志(电子版) ›› 2026, Vol. 16 ›› Issue (04) : 380 -384. doi: 10.3877/cma.j.issn.2095-2015.2026.04.016

病例报告

Cronkhite-Canada综合征病例一例
吴一鸣1,2, 朱佳俊1, 陈平3,()   
  1. 1225000 江苏省,扬州大学
    2215300 江苏省,昆山市中西医结合医院脾胃病科
    3201801 上海交通大学医学院附属瑞金医院北部院区消化内科
  • 收稿日期:2025-02-13 出版日期:2026-08-01
  • 通信作者: 陈平
  • Received:2025-02-13 Published:2026-08-01
引用本文:

吴一鸣, 朱佳俊, 陈平. Cronkhite-Canada综合征病例一例[J/OL]. 中华消化病与影像杂志(电子版), 2026, 16(04): 380-384.

图1 Cronkhite-Canada综合征患者第一次电子胃镜检查 1A:食管通畅,黏膜光滑完整,蠕动扩张度可,贲门黏膜充血,条索状糜烂灶伴陈旧性血痂;1B:黏液湖见咖啡色液体附着,胃底散见条片状糜烂、发红及咖啡斑附着;1C:胃体黏膜皱襞呈脑回状,黏膜充血、水肿,见散在条索状糜烂灶伴陈旧性血痂附着;1D、1E:胃角多发颗粒样发红增生,局部见咖啡斑附着;1F:胃角黏膜粗糙,见颗粒状隆起、发红,散见咖啡斑附着。胃窦黏膜散见咖啡斑附着,黏膜呈颗粒样增生、结节样状隆起;1G、1H:十二指肠球部黏膜充血水肿,散见霜斑样溃疡,十二指肠降部散见霜斑样溃疡
图2 Cronkhite-Canada综合征患者电子胃镜下取活检病理学检查(HE染色,×400) 2A、2B:胃窦黏膜慢性炎,间质内梭形细胞增生伴水肿;2C、2D:胃角黏膜慢性炎,间质内梭形细胞增生伴水肿
图3 Cronkhite-Canada综合征患者第一次电子结肠镜检查 3A:末端回肠未见明显异常;3B:回盲部见弥漫性颗粒样、结节样隆起,表面充血、发红;3C升结肠见弥漫性颗粒样、结节样隆起,表面充血、发红;3D、3E:横结肠见弥漫性颗粒样、结节样隆起,表面充血、发红。3F~3H:降结肠、乙状结肠、直肠见弥漫性颗粒样、结节样隆起,表面充血、发红
图4 Cronkhite-Canada综合征患者电子结肠镜下取活检病理学检查(HE染色,×400) 4A、4B:回盲部黏膜急慢性炎伴浅表糜烂;4C、4D:乙状结肠黏膜急慢性炎伴浅表糜烂
图5 Cronkhite-Canada综合征患者第二次电子结肠镜检查 5A:循腔进镜到达回肠末端,末端回肠黏膜见散在斑片状充血、隆起糜烂。退镜观察见回盲部弥漫密布颗粒样、息肉样隆起,回盲瓣呈唇形,阑尾窝存在;5A~5F:分别见升结肠、横结肠、降结肠、乙状结肠、直肠黏膜呈密布颗粒样、结节样隆起,表面充血
图6 Cronkhite-Canada综合征患者第二次电子胃镜检查 6A:胃窦黏膜尚光滑,黏膜略红肿;6B:胃体黏膜皱襞呈脑回状,黏膜略充血、水肿
图7 Cronkhite-Canada综合征患者第三次电子结肠镜检查 7A~7C:分别见横结肠、降结肠、直肠黏膜层光滑,血管纹理清晰,黏膜面未见明显异常
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