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中华消化病与影像杂志(电子版) ›› 2018, Vol. 08 ›› Issue (02) : 49 -52. doi: 10.3877/cma.j.issn.2095-2015.2018.02.001

所属专题: 文献

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溃疡性结肠炎各阶段治疗策略
张智高1, 王要军1,()   
  1. 1. 261000 山东潍坊,阳光融和医院消化内科
  • 收稿日期:2017-12-11 出版日期:2018-04-01
  • 通信作者: 王要军

Treatment strategy of ulcerative colitis in different stages

Zhigao Zhang1, Yaojun Wang1,()   

  1. 1. Department of Gastroenterology, Sunshine Union Hospital, Weifang 261000, China
  • Received:2017-12-11 Published:2018-04-01
  • Corresponding author: Yaojun Wang
  • About author:
    Corresponding author: Wang Yaojun, Email:
引用本文:

张智高, 王要军. 溃疡性结肠炎各阶段治疗策略[J/OL]. 中华消化病与影像杂志(电子版), 2018, 08(02): 49-52.

Zhigao Zhang, Yaojun Wang. Treatment strategy of ulcerative colitis in different stages[J/OL]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2018, 08(02): 49-52.

目的

溃疡性结肠炎(ulcerative colitis,UC)是基于多因素影响而产生的结肠非特异性炎症,目前尚无特效方法治愈。该病表现复杂、转归复杂、治疗方案复杂,对医师的临床技能要求很高。本文针对UC不同阶段表现以及处理原则及手段进行剖析,并结合自身经验对UC不同阶段的治疗方案进行点评、阐述。

Ulcerative colitis is based on many factors, resulting in nonspecific inflammation of the colon, and there is no specific method to cure.The symptoms of the disease are complex, and the outcome and treatment of it are complex too, which has high requirement of clinical skills for clinical doctors.This review analyzes the manifestations and treatment principles of ulcerative colitis in different stages, and aims to comment and elaborate the therapeutic schedules in different stages according to author′s own experience.

1
Ng SC.Emerging leadership lecture: inflammatory bowel disease in Asia: emergence of a " Western" disease[J]. J Gastroenterol Hepatol, 2015, 30(3): 440-445.
2
Furfaro F, Bezzio C, Ardizzone S, et al.Overview of biological therapy in ulcerative colitis: current and future directions[J]. J Gastrointestin Liver Dis, 2015, 24(2): 203-213.
3
Sales-Campos H, Basso PJ, Alves VB, et al.Classical and recent advances in the treatment of infl ammatorybowel diseases[J]. Braz J Med Biol Res, 2015, 48(2): 96-107.
4
Turner D, Walsh CM, Steinhart AH, et al.Response to cortico-steroids in severe ulcerative colitis: a systematic review of the literature and a meta-regression[J]. Clin Gastroenterol Hepatol, 2007, 5(1): 103-110.
5
Engel MA, Neurath MF.New pathophysiological insights and modern treatment of IBD[J]. J Gastroenterol, 2010, 45(6): 571-583.
6
Regueiro M, Loftus EV Jr, Steinhart AH, et al.Medical manage-ment of left-sided ulcerative colitis and ulcerative proctitis: critical evalu-ation of therapeutic trials[J]. Inflamm Bowel Dis, 2006, 12(10): 979-994.
7
Danese S, Siegel CA, Peyrin-Biroulet L. Review article: integrating budesonide-MMX into treatment algorithms for mild-to-moderate ulcerative colitis[J]. Aliment Pharmacol Ther, 2014, 39(10): 1095-1103.
8
Leblanc S, Allez M, Seksik P, et al.GETAID.Successive treatment with cyclosporine and infliximab in steroid-refractory ulcerative colitis[J]. Am J Gastroenterol, 2011, 106(4): 771-777.
9
Feuerstein JD, Cheifetz AS.Ulcerative colitis: epidemiology, diagnosis, and management[J]. Mayo Clin Proc, 2014, 89(11): 1553-1163.
10
Marteau P, Probert CS, Lindgren S, et al.Combined oral and enema treatment with Pentasa(mesalazine)is superior to oral therapy alone in patients with extensive mild/moderate active ulcerative colitis: a randomised, double blind, placebo controlled study[J]. Gut, 2005, 54(7): 960-965.
11
Safdi M, DeMicco M, Sninsky C, et al.A double-blind comparison of oral versus rectal mesalamine versus combination therapy in the treatment of distal ulcerative colitis[J]. Am J Gastroenterol, 1997, 92(10): 1867-1871.
12
Hanauer S, Good LI, Goodman MW, et al.Long-term use of mesalamine(Rowasa)suppositories in remission maintenance of ulcerative proctitis[J]. Am J Gastroenterol, 2000, 95(7): 1749-1754.
13
D′Albasio G, Pacini F, Camarri E, et al.Combined therapy with 5-ami-nosalicylic acid tablets and enemas for maintaining remission in ulcer-ative colitis: a randomized double-blind study[J]. Am J Gastroenterol, 1997, 92(7): 1143-1147.
14
Ford AC, Bernstein CN, Khan KJ, et al.Glucocorticosteroid therapy in inflammatory bowel disease: systematic review and meta-analysis[J]. Am J Gastroenterol, 2011, 106(4): 590-599.
15
刘敏纹,韩玮等.重度溃疡性结肠炎糖皮质激素治疗反应及其影响因素分析[J].安徽医科大学学报,2014,49(5): 648-652.
16
Khan KJ, Dubinsky MC, Ford AC, et al.Efficacy of immunosuppressive therapy for inflammatory bowel dis-ease: a systematic review and meta-analysis[J]. Am J Gastroenterol, 2011, 106(4): 630-642.
17
Ford AC, Sandborn WJ, Khan KJ, et al.Efficacy of biological therapies in inflammatory bowel disease: systematic review and meta-analysis[J]. Am J Gastroenterol, 2011, 106(4): 644-659.
18
Kornbluth A, Sachar DB.Practice Parameters Committee of the Ameri-can College of Gastroenterology.Ulcerative colitis practice guidelines in adults[J]. Am J Gastroenterol, 2010, 105(3): 501-523.
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