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中华消化病与影像杂志(电子版) ›› 2020, Vol. 10 ›› Issue (03) : 132 -135. doi: 10.3877/cma.j.issn.2095-2015.2020.03.009

所属专题: 经典病例 经典病例 文献

病例报告

原发性肝脏神经内分泌癌并肝胆期低信号异常灌注一例及文献复习
秦响1, 王小龙1, 高晶晶1, 郭楠1, 李绍东1,()   
  1. 1. 221000 徐州医科大学附属医院影像科
  • 收稿日期:2020-03-12 出版日期:2020-06-01
  • 通信作者: 李绍东
  • Received:2020-03-12 Published:2020-06-01
引用本文:

秦响, 王小龙, 高晶晶, 郭楠, 李绍东. 原发性肝脏神经内分泌癌并肝胆期低信号异常灌注一例及文献复习[J]. 中华消化病与影像杂志(电子版), 2020, 10(03): 132-135.

图1 该患者超声表现。示肝左内叶不均质低回声团
图2 该患者上腹部CT表现。图A为平扫示肝左内叶团片状低密度影(箭头所示);图B示增强动脉期病灶周围相对高强化,中央低强化(箭头所示);图C示门脉期强化减低但仍显示相对肝实质高强化(箭头所示)
图3 该患者MRI表现。图A~C示肝左内叶占位增强(箭头所示);图A示动脉期肿瘤周边强化明显;图B示静脉期强化程度减低,图C示肝胆期低信号;图D~F示肝右叶斑片状异常信号(箭头所示);图D示T2WI高信号;图E示动脉期明显强化;图F示肝胆期低信号
图4 该患者PET CT表现。肝左内叶占位,葡萄糖代谢增高,肝右叶未示明显葡萄糖高代谢灶,全身其他脏器均未示明显葡萄糖高代谢灶。图A为CT平扫图像;图B为PET融合图像;图C为冠状位PET的MIP图;图D为轴位PET的MIP图
图5 该患者病理表现。肿瘤细胞呈器官样生长,体积较大,核泡状,核分裂像约17个/HPF,Ki67(+,热点区约60%)、CGA阳性。图A为HE染色,×400;图B、C为免疫组化染色,×400
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