调查厦门市梧村社区小学生HBV感染的流行病学及免疫接种情况，为本地区乙型肝炎综合防控策略提供参考依据。

对厦门梧村社区三小学共2 722名小学生进行普查，用酶联免疫吸附法(ELISA)检测乙型肝炎血清标志物，6个月后统计免疫接种情况。

HBsAg阳性率为2.8%，HBsAb阳性率为28.4%，随年龄增长呈下降趋势，年龄6～7岁组明显高于≥10岁组。三小学中梧村小学乙型肝炎感染率最高，实验二小感染率最低。共发现HBV"小三阳"51例，梧村小学共23例(45%)，HBV"大三阳"0例。所有小学生于出生后0、1、6个月全部接种三针次乙型肝炎疫苗，目前高抗体梯度7人(0.3%)，低抗体滴度766人(28.1%)。6月后梧村、实验、东埔三小学实际免疫接种率分别为28.67%、62.33%、10.71%，差异有统计学意义(χ²＝294.9，P<0.01)。

厦门梧村社区小学生具有HBsAg阳性率低，但保护性抗体HBsAb阳性率、抗体滴度及总体免疫接种率低等特点，且HBsAb的血浆水平随着年龄增长呈下降趋势。所有HbsAg阴性及HBsAb抗体滴度低的小学生应再次免疫接种，尤其是大年龄组小学生，对提高厦门市地区对小学生乙型肝炎防控意义重大。

To investigate the prevalence of hepatitis B virus(HBV)infecting and immunization status of primary school students in Wucun community of Xiamen city, and to provide reference for comprehensive prevention and control strategy of hepatitis B in this region.

A census method was used for a total of 2 722 cases of primary school students in three primary schools in Wucun community of Xiamen city.HBV serum markers were detected by enzyme-linked immunosorbent assay(ELISA), and the immunization status was counted after six months.

The positive rate of HBsAg was 2.8%, and the positive rate of HBsAb was 28.4%, both of which showed a decreasing trend with the increase of age, and the age of 6~7 group was significantly higher than the group of age of 10 and above.In the three primary schools, the infection rate of hepatitis B in Wucun Primary School was the highest, and the infection rate of the Second Experimental Primary School was the lowest.A total of 51 cases were found in HBV "Small Positive" , Wucun Primary School with 23 cases, which accounted for almost 45% of the 51 cases.None of cases were found in HBV "Big Positive" . All pupils were vaccinated with hepatitis B vaccine three times in 0, 1 and 6 months after birth, at present, high antibody titer was found in 7 person(0.3%), and low antibody titer was found in 766 person(28.1%). After six months, the actual immunization rates of Wucun Primary School, Second Experimental Primary School and Dongpu Primary School were 28.67%, 62.33% and 10.71% respectively, with a statistically significant difference(χ²=294.9, P<0.01).

The three primary school students in Wucun community of Xiamen city have the characteristics of lower HBsAg positive rate, and lower HBsAb positive rate, antibody titer and overall immunization rate, and the serum level of HBsAb has the trend to decrease with the increasing of age.All of the students with HBsAg negative or low level of HBsAb should receive additional immunization, especially those large age group students, which is of great significance to improve the prevention and control of HBV infection among primary school students in Xiamen.