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中华消化病与影像杂志(电子版) ›› 2022, Vol. 12 ›› Issue (03) : 129 -132. doi: 10.3877/cma.j.issn.2095-2015.2022.03.001

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重视脂肪胰的基础和临床研究
朱国英1, 陈利2,(), 丁永年3, 杨长青4, 朱风尚5,()   
  1. 1. 200060 上海,同济大学附属普陀人民医院临床营养科
    2. 830000 乌鲁木齐,省部共建中亚高发病成因与防治国家重点实验室;200065 上海,同济大学附属同济医院消化科
    3. 830063 乌鲁木齐,新疆医科大学第二附属医院消化科
    4. 830000 乌鲁木齐,省部共建中亚高发病成因与防治国家重点实验室
    5. 830000 乌鲁木齐,省部共建中亚高发病成因与防治国家重点实验室;200065 上海,同济大学附属同济医院消化科;830063 乌鲁木齐,新疆医科大学第二附属医院消化科
  • 收稿日期:2021-12-25 出版日期:2022-06-01
  • 通信作者: 陈利, 朱风尚
  • 基金资助:
    省部共建中亚高发病成因与防治国家重点实验室开放课题(SKL-HIDCA-2021-DX9); 新疆维吾尔自治区科技厅科技援疆项目计划(2021E02075); 上海市临床重点专科建设项目基金(shslczdzk06801)

Pay attention to basic and clinical research of fatty pancreas

Guoying Zhu1, Li Chen2,(), Yongnian Ding3, Changqing Yang4, Fengshang Zhu5,()   

  1. 1. Department of Clinical Nutrition, Putuo People′s Hospital, Tongji University, Shanghai 200060, China
    2. State Key Laboratory of Pathogenesis and Prevention of Middle Altitude Disease Jointly Established by Provincial and Ministry, Urumchi 830000, China; Department of Gastroenterology, Tongji Hospital of Tongji University, Shanghai 200065, China
    3. Department of Gastroenterology, Second Affiliated Hospital of Xinjiang Medical University, Urumchi 830063, China
    4. State Key Laboratory of Pathogenesis and Prevention of Middle Altitude Disease Jointly Established by Provincial and Ministry, Urumchi 830000, China
    5. State Key Laboratory of Pathogenesis and Prevention of Middle Altitude Disease Jointly Established by Provincial and Ministry, Urumchi 830000, China; Department of Gastroenterology, Tongji Hospital of Tongji University, Shanghai 200065, China; Department of Gastroenterology, Second Affiliated Hospital of Xinjiang Medical University, Urumchi 830063, China
  • Received:2021-12-25 Published:2022-06-01
  • Corresponding author: Li Chen, Fengshang Zhu
引用本文:

朱国英, 陈利, 丁永年, 杨长青, 朱风尚. 重视脂肪胰的基础和临床研究[J]. 中华消化病与影像杂志(电子版), 2022, 12(03): 129-132.

Guoying Zhu, Li Chen, Yongnian Ding, Changqing Yang, Fengshang Zhu. Pay attention to basic and clinical research of fatty pancreas[J]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2022, 12(03): 129-132.

脂肪胰作为一种肥胖相关代谢综合征(MS)组份并不罕见,不仅与MS相关疾病关系密切,而且在胰腺炎、胰腺癌和胰瘘风险中起重要作用。相较于肝脏组织,胰腺对脂肪沉积更敏感,脂肪胰发生早于代谢相关脂肪性肝病。但目前对脂肪胰重视度和知晓度不容乐观。本文概述了脂肪胰的发病机制、病理生理学、与其他临床疾病的关系、诊断预防和治疗现状,阐述了目前对其了解的局限性和争议性,以引起对其基础和临床研究的重视。

Fatty pancreas(FP)is not uncommon as a component of obesity-related metabolic syndrome.It is not only closely related to metabolic syndrome-related diseases, but also plays a causative role in the risk of pancreatitis, pancreatic cancer and pancreatic fistula.Compared with metabolic dysfunction-associated fatty liver disease(MAFLD), current status is not optimistic about the degree of attention and awareness of FP that even occurs earlier than MAFLD.This editorial outlines several important issues of FP in pathogenesis, pathophysiology, correlation with other clinical diseases, diagnosis, prevention and treatment status, and summarizes the limitations and controversies of the current understanding in FP, in order to attract attention to its basic and clinical research.

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