探讨双气囊小肠镜(DBE)及小肠CT造影(CTE)在小肠疾病中的诊断价值，分析CTE结果阴性的患者出现DBE结果阳性的预测因素。

纳入2018年5月至2022年5月因怀疑小肠疾病就诊安徽医科大学第一附属医院行CTE及DBE检查的患者1013例，收集相关资料并比较两种检查方法检出率、诊断率及对小肠疾病诊断价值的差别。

以DBE结果为参考标准，CTE的灵敏度为89.6%，特异度为49.1%，阳性预测值为93.6%，阴性预测值为36.1%。DBE的总检出率及总诊断率均高于CTE。多因素分析显示，年龄<60岁、贫血、低白蛋白血症是CTE结果阴性的患者出现DBE结果阳性的预测因素。CTE结果阴性而DBE结果阳性的患者中，镜下表现以小肠炎症、糜烂和溃疡性病变最常见，其次为小肠血管性病变。

在CTE结果阴性的患者中，年龄<60岁、贫血和低白蛋白血症的患者出现DBE结果阳性的可能性更大。在怀疑小肠黏膜病变、小肠出血时，若CTE结果阴性，应进一步行DBE检查以明确诊断。

To explore the diagnostic value of double-balloon enteroscopy(DBE)and computed tomography enterography(CTE)in small bowel diseases, and to analyze the predictive factors of DBE positive results in patients with negative CTE results.

A total of 1013 patients with suspected small bowel disease underwent CTE and DBE examination were enrolled, and relevant data were collected and the difference in detection rate, diagnosis rate and diagnostic value of the two examination methods for small bowel disease was compared.

Taking DBE results as the reference standard, the sensitivity of CTE was 89.6%, the specificity was 49.1%, the positive predictive value was 93.6%, and the negative predictive value was 36.1%.The overall detection rate and total diagnostic rate of DBE were higher than those of CTE.Multivariate analysis showed that age<60 years, anemia, and hypoalbuminemia were predictors of positive DBE results in patients with negative CTE.In patients with negative CTE and positive DBE, microscopic findings were small bowel inflammation, erosion, and ulcerative lesions, followed by small bowel vascular lesions.

Among patients with negative CTE results, patients aged<60 years with anemia and hypoalbuminemia are more likely to be DBE positive.When small bowel mucosal lesions or small bowel bleeding are suspected, if CTE is negative, DBE is still recommended to confirm the diagnosis.