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中华消化病与影像杂志(电子版) ›› 2024, Vol. 14 ›› Issue (05) : 422 -425. doi: 10.3877/cma.j.issn.2095-2015.2024.05.008

论著

胃癌旁肿瘤沉积与CT影像学特征、血清指标及病理特征的关联性分析
甘曦1, 廖鑫1,()   
  1. 1. 400050 重庆市九龙坡区人民医院放射科
  • 收稿日期:2023-10-19 出版日期:2024-10-01
  • 通信作者: 廖鑫

Correlation analysis of tumor deposition near gastric cancer with CT imaging characteristics, serum indexes and pathological characteristics

Xi Gan1, Xin Liao1,()   

  1. 1. Department of Radiology, Jiulongpo District People's Hospital of Chongqing, Chongqing 400050, China
  • Received:2023-10-19 Published:2024-10-01
  • Corresponding author: Xin Liao
引用本文:

甘曦, 廖鑫. 胃癌旁肿瘤沉积与CT影像学特征、血清指标及病理特征的关联性分析[J/OL]. 中华消化病与影像杂志(电子版), 2024, 14(05): 422-425.

Xi Gan, Xin Liao. Correlation analysis of tumor deposition near gastric cancer with CT imaging characteristics, serum indexes and pathological characteristics[J/OL]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2024, 14(05): 422-425.

目的

分析胃癌旁肿瘤沉积与CT影像学特征、血清指标及病理特征的关联性。

方法

选取重庆市九龙坡区人民医院2020年1月至2023年1月收治的93例经病理检查明确胃癌诊断的患者,按照其肿瘤沉积情况,将患者分别纳入阳性组、阴性组。比较2组患者CT影像学特征、血清指标、病理特征的差异,使用Logistic多因素回归分析,评估上述特征与肿瘤沉积的关联。

结果

93例患者中,26例检出肿瘤沉积,肿瘤沉积阳性率为27.96%。阳性组与阴性组影像学分期、病灶静脉期强化特点比较,差异有统计学意义(P<0.05)。阳性组与阴性组血清癌胚抗原比较,差异有统计学意义(P<0.05)。阳性组与阴性组病理分期、脉管侵犯特点比较,差异有统计学意义(P<0.05)。Logistic多因素回归模型分析结果示,影像学分期T3~T4期、病理分期N3期、存在脉管侵犯为肿瘤沉积的独立危险因素(P<0.05)。

结论

部分胃癌患者存在癌旁肿瘤沉积,更高的影像学分期、病理分期以及脉管侵犯的发生均可能与肿瘤沉积有关。

Objective

To analyze the correlation between tumor deposition near gastric cancer and CT imaging features, serum indexes and pathological features.

Methods

A total of 93 patients with gastric cancer diagnosed by pathological examination in Jiulongpo District People's Hospital of Chongqing from January 2020 to January 2023 were selected and divided into positive group and negative group according to their tumor deposition. The differences of CT imaging features, serum indexes and pathological features between the two groups were compared, and the relationship between the above features and tumor deposition was evaluated by Logistic multivariate regression analysis.

Results

Among 93 patients, 26 patients were found with tumor deposition, and the positive rate of tumor deposition was 27.96%. There was statistically significant difference between the positive group and the negative group in imaging staging and enhancement characteristics of venous phase (P<0.05). There was statistically significant difference in serum CEA between the positive group and the negative group (P<0.05). There were statistically significant differences between the positive group and the negative group in pathological stages and vascular invasion characteristics (P<0.05). Logistic multivariate regression model analysis showed that imaging stage T3-4, pathological stage N3 and vascular invasion were independent risk factors for tumor deposition (P<0.05).

Conclusion

Some patients with gastric cancer have tumor deposition near cancer, and higher imaging staging, pathological staging and vascular invasion may be related to tumor deposition.

表1 2组患者CT影像学特征比较[例(%)]
表2 2组患者血清指标差异比较[例(%)]
表3 2组患者临床及病理特征比较[例(%)]
表4 多因素回归模型赋值表
表5 影响胃癌旁肿瘤沉积的多因素回归分析结果
[1]
Liang Y, Wu L, Liu L, et al. Impact of extranodal tumor deposits on prognosis and N stage in gastric cancer[J]. Surgery, 2019, 166(3): 305-313.
[2]
王晨, 李绍东, 孟闫凯, 等. 结肠癌病理T分期, N分期与肿瘤沉积的相关性[J]. 临床与病理杂志, 2020, 40(2): 310-315.
[3]
Wenquan L, Yuhua L, Jianxin C, et al. Tumor deposit serves as a prognostic marker in gastric cancer: A propensity score‐matched analysis comparing survival outcomes[J]. Cancer Med, 2020, 9(10): 3268-3277.
[4]
Li M, Xu G, Chen Q, et al. Computed tomography-based radiomics nomogram for the preoperative prediction of tumor deposits and clinical outcomes in colon cancer: a multicenter study[J]. Acad Radiol, 2023, 30(8): 1572-1583.
[5]
杨桂才, 朱福成. 基于MSCT回归模型术前诊断结直肠癌患者癌旁肿瘤沉积的价值[J]. 分子影像学杂志, 2022, 45(3): 419-423.
[6]
潘绵鸾, 唐姝丹, 曾文, 等. 44例肺泡蛋白沉积症患者临床特征与血清肿瘤标志物及乳酸脱氢酶相关性分析[J]. 国际呼吸杂志, 2020, 40(16): 1232-1237.
[7]
Zhang G, Zhang C, Wang L, et al. The prognostic value of tumor deposits and the impact on the TNM classification system in esophageal cancer patients[J]. J SurgOncol, 2021, 123(4): 891-903.
[8]
Wu L, Feng Y, Wu Z, et al. Survival outcomes of adjuvant taxanes, platinum plus fluoropyrimidines versus platinum and fluoropyrimidines for gastric cancer patients after D2 gastrectomy: a retrospective propensity score-matched analysis[J]. World J Surg Oncol, 2021, 19(1): 1-12.
[9]
江小云, 赵铭, 陈淑君, 等. 螺旋CT诊断老年胃癌患者术前分期的价值[J]. 分子影像学杂志, 2021, 44(1): 151-154.
[10]
Chen Y, Jia Y, Peng Z, et al. The prognostic role of tumor size in stage T1 gastric cancer[J]. World J Surg Oncol, 2022, 20(1): 1-8.
[11]
Lee I S, Lee H, Hur H, et al. Transcriptomic profiling identifies a risk stratification signature for predicting peritoneal recurrence and micrometastasis in gastric cancer[J]. Clin Cancer Res, 2021, 27(8): 2292-2300.
[12]
赵瑾, 陈海燕, 丁信法, 等. 胃癌MSCT表现和临床病理特征与HER2表达的相关性研究[J]. 实用肿瘤杂志, 2020, 35(3): 201-207.
[13]
曾艺辉, 吕国义, 喻汉华, 等. 多层螺旋CT在胃癌术前分期中的应用[J]. 中国老年学杂志, 2019, 39(12): 2879-2882.
[14]
Lin HW, Loh EW, Shen SC, et al. Gastrectomy with or without omentectomy for gastric cancer: A systematic review and meta-analysis[J]. Surgery, 2022, 171(5): 1281-1289.
[15]
Yang TS, Wang XF, Fairweather M, et al. The survival benefit from the addition of radiation to chemotherapy in gastric cancer patients following surgical resection[J]. Clin Oncol 2020, 32(2): 110-120.
[16]
许舒航, 冯玲玲, 陈永明, 等. 多层螺旋CT对胃癌各淋巴结分区淋巴结转移诊断敏感性研究[J]. 中华胃肠外科杂志, 2019, 22(10): 984-989.
[17]
Sun Y, Deng Y, Xu M, et al. A refined prediction of early recurrence combining tumor deposits in patients with resected rectal mucinous adenocarcinoma[J]. Surg Today, 2023, 53(7): 762-772.
[18]
de Jongh C, Triemstra L, van Der Veen A, et al. Pattern of lymph node metastases in gastric cancer: a side-study of the multicenter LOGICA-trial[J]. Gastric Cancer, 2022, 25(6): 1060-1072.
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