切换至 "中华医学电子期刊资源库"

中华消化病与影像杂志(电子版) ›› 2021, Vol. 11 ›› Issue (05) : 226 -228. doi: 10.3877/cma.j.issn.2095-2015.2021.05.010

综述

射频消融在早期肝癌治疗中的应用进展
李佳莹1, 张秋丽1,(), 张修礼2   
  1. 1. 457000 河南大学附属濮阳市人民医院消化内科
    2. 100853 北京,解放军总医院第一医学中心消化内科
  • 收稿日期:2021-03-23 出版日期:2021-10-01
  • 通信作者: 张秋丽

Application progress of radiofrequency ablation in the treatment of early hepatocellular carcinoma

Jiaying Li1, Qiuli Zhang1,(), Xiuli Zhang2   

  1. 1. Department of Gastroenterology, Puyang People′s Hospital Affiliated to Henan University, Puyang457000, China
    2. Department of Gastroenterology, First Medical Center of Chinese PLA General Hosptial, Beijing 100853, China
  • Received:2021-03-23 Published:2021-10-01
  • Corresponding author: Qiuli Zhang
引用本文:

李佳莹, 张秋丽, 张修礼. 射频消融在早期肝癌治疗中的应用进展[J/OL]. 中华消化病与影像杂志(电子版), 2021, 11(05): 226-228.

Jiaying Li, Qiuli Zhang, Xiuli Zhang. Application progress of radiofrequency ablation in the treatment of early hepatocellular carcinoma[J/OL]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2021, 11(05): 226-228.

目前早期肝癌常选择的治疗方式有射频消融术(RFA)、肝动脉介入化疗栓塞术(TACE)以及根治性肝切除术。近年来的研究表明,RFA有着有效、并发症少、可重复操作、住院时间短及花费少等优势,被认为是早期局灶性肝癌的首选治疗方式。但在相当长的一段时间内,RFA有着较高的肿瘤复发率。本文总结了近年来RFA在局灶性肝癌治疗中的最新的应用进展。

Currently, the most commonly selected treatments for early liver cancer are radiofrequency ablation(RFA), transcatheter arterial chemoembolization(TACE), and radical hepatectomy.Research in recent years has shown that RFA has the advantages of effectiveness, fewer complications, repeatable operations, short hospital stay and less cost, and is considered to be the first choice for the treatment of early focal liver cancer.But for a long period of time, RFA has a high tumor recurrence rate.This article summarizes the latest progress in the application of RFA in the treatment of focal liver cancer in recent years.

1
Bray F, Ferlay J, Soerjomataram I, et al.Global cancer statistics 2018:GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J].CA Cancer J Clin,2018,68(6):394-424.
2
Tashiro H, Aikata H, Waki K,et al.Treatment strategy for early hepatocellular carcinomas:comparison of radiofrequency ablation with or without transcatheter arterial chemoembolization and surgical resection[J].J Surg Oncol,2011,104(1):3-9.
3
Izzo F, Granata V, Grassi R, et al.Radiofrequency Ablation and Microwave Ablation in Liver Tumors:An Update[J].Oncologist,2019,24(10):e990-e1005.
4
Jin S, Tan S, Peng W, et al.Radiofrequency ablation versus laparoscopic hepatectomy for treatment of hepatocellular carcinoma:a systematic review and meta-analysis[J].World J Surg Oncol,2020,18(1):199.
5
Ganne-Carrié N, Nault JC, Ziol M, et al.Predicting recurrence following radiofrequency percutaneous ablation for hepatocellular carcinoma[J].Hepat Oncol,2014,1(4):395-408.
6
Harrison LE, Koneru B, Baramipour P, et al.Locoregional recur-rences are frequent after radiofrequency ablation for hepatocellular carcinoma[J].J Am Coll Surg,2003,197(5):759-764.
7
Cohen GS, Black M.Multidisciplinary management of hepatocellular carcinoma:a model for therapy[J].J Multidiscip Healthc,2013,6:189-95.
8
Wang F, Numata K, Nihonmatsu H, et al.Intraprocedurally EOB-MRI/US fusion imaging focusing on hepatobiliary phase findings can help to reduce the recurrence of hepatocellular carcinoma after radiofrequency ablation[J].IntJ Hyperthermia,2020,37(1):1149-1158.
9
Li Q, Chen K, Huang W, et al.Minimally invasive photothermal ablation assisted by laparoscopy as an effective preoperative neoadjuvant treatment for orthotopic hepatocellular carcinoma[J].Cancer Lett,2021,496:169-178.
10
Schullian P, Laimer G, Putzer D, et al.Stereotactic radiofrequency ablation as first-line treatment of recurrent HCC following hepatic resection[J].Eur J Surg Oncol,2020,46(8):1503-1509.
11
Solbiati L, Ierace T, Gennaro N, et al.Percutaneous radiofrequency ablation of HCC:reduced ablation duration and increased ablation size using single,internally cooled electrodes with an optimized pulsing algorithm[J].Int J Hyperthermia,2020,37(1):861-867.
12
Han TS, Ban HS, Hur K, et al.The Epigenetic Regulation of HCC Metastasis[J].Int J Mol Sci,2018,19(12):3978.
13
Lassandro G, Picchi SG, Bianco A,et al.Effectiveness and safety in radiofrequency ablation of pulmonary metastases from HCC:a five years study[J].Med Oncol,2020,37(4):25.
14
Cui Y, Wu X, Lin C,et al.AKIP1 promotes early recurrence of hepatocellular carcinoma through activating the Wnt/β-catenin/CBP signaling pathway[J].Oncogene,2019,38(27):5516-5529.
15
Dong P, Wang X, Liu L,et al.Dampened VEPH1 activates mTORC1 signaling by weakening the TSC1/TSC2 association in hepatocellular carcinoma[J].J Hepatol,2020,28:S0168-8278(20)30400-1.
16
Zhao M, Wang Y, Liu Y,et al.C7 peptide inhibits hepatocellular carcinoma metastasis by targeting the HGF/c-Met signaling pathway[J].Cancer Biol Ther,2019,20(12):1430-1442.
17
Greten TF, Manns MP, Korangy F.Immunotherapy of hepatocellular carcinoma[J].J Hepatol,2006,45(6):868-878.
18
Rochigneux P, Nault JC, Mallet F, et al.Dynamic of systemic immunity and its impact on tumor recurrence after radiofrequency ablation of hepatocellular carcinoma[J].Oncoimmunology,2019,8(8):1615818.
19
Wu H, Li SS, Zhou M,et al.Palliative Radiofrequency Ablation Accelerates the Residual Tumor Progression Through Increasing Tumor-Infiltrating MDSCs and Reducing T-Cell-Mediated Anti-Tumor Immune Responses in Animal Model[J].Front Oncol,2020,10:1308.
20
Bian H, Zheng JS, Nan G,et al.Randomized trial of [131I]metuximab in treatment of hepatocellular carcinoma after percutaneous radiofrequency ablation[J].J Natl Cancer Inst,2014,106(9):dju239.
21
Duffy AG, Ulahannan SV, Makorova-Rusher O,et al.Tremelimumab in combination with ablation in patients with advanced hepatocellular carcinoma[J].J Hepatol,2017,66(3):545-551.
22
吴沛宏,陈奇峰,李旺.肝细胞癌微创与多学科综合诊疗——2018广州共识[J].临床肝胆病杂志,2019,35(10):2176-2184.
23
Li H, Meng X, Zhang D, et al.Ginkgolic acid suppresses the invasion of HepG2 cells via downregulation of HGF/c-Met signaling[J].Oncol Rep,2019,41(1):369-376.
24
Shao J, Shi CJ, Li Y,et al.LincROR Mediates the Suppressive Effects of Curcumin on Hepatocellular Carcinoma Through Inactivating Wnt/β-Catenin Signaling[J].Front Pharmacol,2020,11:847.
25
Anwanwan D, Singh SK, Singh S, et al.Challenges in liver cancer and possible treatment approaches[J].Biochim Biophys Acta Rev Cancer,2020,1873(1):188314.
[1] . 绝经激素治疗与卵巢癌相关性的探讨[J/OL]. 中华妇幼临床医学杂志(电子版), 2024, 20(01): 125-.
[2] 汤宏涛, 何坤. 中晚期肝细胞癌介入治疗的进展及前景[J/OL]. 中华普通外科学文献(电子版), 2024, 18(04): 305-308.
[3] 杨建波, 马欢, 黄小梅, 刘华柱. 结肠镜辅助下EMR、CSP和RFA术治疗直径<1cm结直肠息肉的疗效和安全性比较[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 76-79.
[4] 刘世君, 马杰, 师鲁静. 胃癌完整系膜切除术+标准D2根治术治疗进展期胃癌的近中期随访研究[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 27-30.
[5] 高建新, 王啸飞, 于淼, 路夷平. 局部进展期直肠癌新辅助治疗后行ISR术远切缘距离的临床研究[J/OL]. 中华普外科手术学杂志(电子版), 2024, 18(05): 539-543.
[6] 黄莹, 李璇, 刘梦杨, 彭桂林, 徐鑫, 韦兵, 杨超. 靶向联合治疗双肺移植术后KRAS和BRAF基因双突变晚期肺腺癌一例[J/OL]. 中华移植杂志(电子版), 2024, 18(05): 298-301.
[7] 中国器官移植发展基金会器官移植受者健康管理专家委员会, 中国医师协会器官移植医师分会, 中华医学会器官移植学分会, 国家肝脏移植质控中心. 肝移植受者雷帕霉素靶蛋白抑制剂临床应用中国专家共识(2023版)[J/OL]. 中华移植杂志(电子版), 2023, 17(04): 193-204.
[8] 臧宇, 姚胜, 朱新勇, 戎世捧, 田智超. 低温等离子射频消融治疗腹壁疝术后补片感染的临床效果[J/OL]. 中华疝和腹壁外科杂志(电子版), 2024, 18(06): 687-692.
[9] 杨涛, 吕学祥, 李念, 王燕红, 余梦琳, Menglin Yu. 阵发性房颤射频消融术后肺静脉狭窄的临床分析[J/OL]. 中华肺部疾病杂志(电子版), 2023, 16(06): 814-817.
[10] 王晓东, 汪恺, 葛昭, 丁忠祥, 徐骁. 计算机视觉技术在肝癌肝移植疗效提升中的研究进展[J/OL]. 中华肝脏外科手术学电子杂志, 2023, 12(04): 361-366.
[11] 刘华亭, 张媛, 张登文, 王杰, 袁阳. 介入栓塞联合手术切除治疗头皮动静脉畸形的疗效观察[J/OL]. 中华神经创伤外科电子杂志, 2024, 10(05): 273-278.
[12] 莫鹏, 郭杏春, 梁秀娟, 王耀明. 超声引导与CT引导射频消融治疗肝细胞癌患者疗效及预后比较[J/OL]. 中华消化病与影像杂志(电子版), 2024, 14(02): 151-154.
[13] 蒲丹, 龙煊, 周玉龙, 李甘霖. 血清外泌体miR-224对结直肠癌肝转移患者射频消融治疗后复发的预测价值[J/OL]. 中华消化病与影像杂志(电子版), 2024, 14(01): 45-52.
[14] 楚海强, 杨远游, 任刚. 胰腺癌放射治疗联合其他治疗方法的研究进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(04): 392-396.
[15] 王楠钧, 马燕, 李隆松, 牛晓彤, 刘圣圳, 毕雅维, 苏松, 柴宁莉, 令狐恩强. 不同年龄段胃低级别上皮内瘤变患者内镜下射频消融术的疗效对比分析[J/OL]. 中华胃肠内镜电子杂志, 2024, 11(04): 238-242.
阅读次数
全文


摘要


AI


AI小编
你好!我是《中华医学电子期刊资源库》AI小编,有什么可以帮您的吗?