研究自适应性生物反馈训练结合自拟中药方在出口梗阻型便秘（OOC）患者中的应用效果。

选择青岛市城阳区人民医院2023年2月至2024年10月接收的86例OOC患者，按照随机数表法分为观察组及对照组，均43例。对照组采用自适应性生物反馈训练，观察组在对照组基础上结合自拟中药方治疗。比较两组治疗4周后的临床疗效，比较治疗前后的便秘症状评分、便秘患者生活质量问卷（PAC-QOL）、胃肠激素（胆囊收缩素、胃动素、胃泌素、血管活性肠肽）、盆底表面肌电值（快速收缩、10 s持续收缩及耐久收缩的平均波幅）、肛肠动力学（直肠排便感觉阈值、直肠初始感觉阈值、直肠肛门压力梯度），比较治疗期间的不良反应情况。

治疗4周后，观察组总有效率高于对照组（P<0.05）；观察组便秘症状评分、PAC-QOL评分低于对照组（P<0.05），胆囊收缩素、胃动素及胃泌素水平高于对照组（P<0.05），血管活性肠肽水平低于对照组（P<0.05）；观察组快速收缩、10 s持续收缩及耐久收缩的平均波幅均大于对照组（P<0.05）；观察组直肠排便感觉阈值、直肠初始感觉阈值均低于对照组（P<0.05），直肠肛门压力梯度大于对照组直肠肛门压力梯度（P<0.05）；两组均未见明显不良反应。

自适应性生物反馈训练结合自拟中药方对OOC患者的效果显著，能够有效减轻患者症状，提高生活质量，调节胃肠激素分泌，优化肛肠动力学。

To study the effect of adaptive biofeedback training combined with self-designed Chinese prescription in patients with exit obstructive constipation (OOC).

A total of 86 OOC patients admitted to Chengyang District People's Hospital of Qingdao from February 2023 to October 2024 were divided into observation group and control group according to random number table method, with 43 cases in each group. The control group was treated with adaptive biofeedback training, and the observation group was treated with self-designed Chinese prescription on the basis of the control group. The clinical efficacy of two groups of patients after 4 weeks of treatment were compared, the constipation symptom scores before and after treatment, the quality of life questionnaire for constipation patients (PAC-QOL), gastrointestinal hormones (cholecystokinin, motilin, gastrin, vasoactive intestinal peptide), pelvic floor surface electromyography values (average amplitude of rapid contraction, 10 second sustained contraction, and durable contraction), anorectal dynamics (rectal defecation sensation threshold, initial rectal sensation threshold, rectal anal pressure gradient) were compared, and the adverse reactions during treatment were compared.

After 4 weeks of treatment, the total effective rate of observation group was higher than that of control group (P<0.05); the constipation symptom score and PAC-QOL score of the observation group were lower than those of the control group (P<0.05); the levels of cholecystokinin, motilin and gastrin in the observation group were higher than those in the control group (P<0.05), and the level of vasoactive intestinal peptide was lower than that in the control group (P<0.05); the average amplitude of rapid contraction, 10 second sustained contraction and durable contraction in the observation group were higher than those in the control group (P<0.05); the threshold of supportive defecation sensation and initial rectal sensation threshold in the observation group were lower than those in the control group (P<0.05), and the rectal anal pressure gradient was greater than that in the control group (P<0.05). No obvious adverse reactions were observed in both groups.

Adaptive biofeedback training combined with self-designed Chinese prescription has significant effects on OOC patients, which can effectively reduce symptoms, improve quality of life, regulate gastrointestinal hormone secretion, and optimize anorectal dynamics.