通过分析128例行幽门螺杆菌(Helicobacter pylori，Hp)根除患者治疗前后的血脂变化，进一步证实根除Hp能够使血脂趋于正常水平，为动脉粥样硬化的治疗寻找一条新方案。

回顾性分析宁夏回族自治区人民医院2014年1月至2018年1月128例Hp感染患者根除Hp前后的血脂变化情况。

根除Hp后低密度脂蛋白[(3.12±0.65)mmol/L比(2.18±0.60)mmol/L]和甘油三酯[(1.91±0.63)mmol/L比(1.23±0.51)mmol/L]水平相对于治疗前差异有统计学意义(P<0.05)，而根除Hp后极低密度脂蛋白[(0.57±0.25)mmol/L比(0.60±0.27)mmol/L]、高密度脂蛋白[(1.13±0.28)mmol/L比(1.24±0.32)mmol/L]、总胆固醇[(4.30±0.85)mmol/L比(4.16±0.89)mmol/L]水平差异均无统计学意义(P>0.05)。

根除Hp在一定程度上可以改善患者的血脂水平。

To confirm the eradication of Helicobacter pylori(Hp)can make blood lipids to normal level and find a new method for the treatment of atherosclerosis by analyzing the changes of blood lipids in 128 patients before and after the eradication of Hp.

The changes of blood lipids in 128 patients with Hp infection before and after eradication of Hp from January 2014 to January 2018 were retrospectively analyzed in Ningxia Hui Autonomous Region People′s Hospital.

Low density lipoprotein [(2.18±0.60)mmol/L vs.(3.12±0.65)mmol/L]and triglyceride [(1.23±0.51)mmol/L vs.(1.91±0.63)mmol/L]levels were significantly lower after Hp eradication than before treatment(P<0.05), while there were no statistically significant differences in very low-density lipoprotein [(0.57±0.25)mmol/L vs.(0.60±0.27)mmol/L], high-density lipoprotein [(1.13±0.28)mmol/L vs.(1.24±0.32)mmol/L]and total cholesterol [(4.30±0.85)mmol/L vs.(4.16±0.89)mmol/L]levels after Hp eradication(P>0.05).

Eradication of Hp can improve the blood lipid level of patients to a certain extent.