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中华消化病与影像杂志(电子版) ›› 2025, Vol. 15 ›› Issue (04) : 289 -293. doi: 10.3877/cma.j.issn.2095-2015.2025.04.001

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重视肠道气体检测在溃疡性结肠炎中的应用
翟崟皓1, 江学良2,()   
  1. 1250001 济南,山东中医药大学
    2250001 济南,山东中医药大学第二附属医院消化中心
  • 收稿日期:2025-03-31 出版日期:2025-08-01
  • 通信作者: 江学良
  • 基金资助:
    山东省中医药科技项目(M20241905)

Emphasizing the application of intestinal gas detection in ulcerative colitis

Yinhao Zhai1, Xueliang Jiang2,()   

  1. 1Shandong University of Traditional Chinese Medicine, Jinan 250001, China
    2Digestive Center, Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250001, China
  • Received:2025-03-31 Published:2025-08-01
  • Corresponding author: Xueliang Jiang
引用本文:

翟崟皓, 江学良. 重视肠道气体检测在溃疡性结肠炎中的应用[J/OL]. 中华消化病与影像杂志(电子版), 2025, 15(04): 289-293.

Yinhao Zhai, Xueliang Jiang. Emphasizing the application of intestinal gas detection in ulcerative colitis[J/OL]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2025, 15(04): 289-293.

溃疡性结肠炎(UC)是一种反复发作的慢性肠道炎症性疾病,其发病机制涉及肠道菌群失衡、机体免疫异常及肠道代谢紊乱等多个方面。近十年来,肠道气体检测因其无创性、动态监测潜力及对疾病预后的评估作用,已逐渐成为UC研究的热点。本文系统阐述氢气(H2)、甲烷(CH4)、硫化氢(H2S)和一氧化氮(NO)四种关键气体的作用,提出H2/CH4、H2S/NO等多气体比值模型在UC中具有辅助诊断及疗效评估的价值,有助于降低UC诊断的内镜依赖率,为UC的诊疗提供新策略。

Ulcerative colitis (UC) is a chronic relapsing inflammatory bowel disease. Its pathogenesis involves multiple factors including gut microbiota imbalance, immune dysfunction, and metabolic disturbances in the intestine. Intestinal gas detection has recently emerged as a research focus in UC due to its non-invasive nature, potential for dynamic monitoring, and ability to assess disease prognosis. This study systematically examines four key gases: hydrogen (H2), methane (CH4), hydrogen sulfide (H2S), and nitric oxide (NO). We propose that multi-gas ratio models (such as H2/CH4 and H2S/NO) show diagnostic and therapeutic evaluation potential in UC. These models could reduce dependence on endoscopic examinations while providing new strategies for UC diagnosis and treatment management.

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