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中华消化病与影像杂志(电子版) ›› 2026, Vol. 16 ›› Issue (01) : 91 -96. doi: 10.3877/cma.j.issn.2095-2015.2026.01.016

综述

胰腺脂肪浸润与急性胰腺炎相关性的研究进展
杨满慧1, 陈平2,()   
  1. 1215400 江苏苏州,上海交通大学医学院附属瑞金医院太仓分院,太仓市娄江新城医院消化内科
    2201801 上海交通大学医学院附属瑞金医院北部院区消化内科
  • 收稿日期:2025-01-16 出版日期:2026-02-01
  • 通信作者: 陈平

Research progress on the association between pancreatic fatty infiltration and acute pancreatitis

Manhui Yang1, Ping Chen2,()   

  1. 1Department of Gastroenterology, Ruijin Hospital Taicang Branch, Shanghai Jiao Tong University School of Medicine, Taicang Loujiang New City Hospital, Suzhou 215400, China
    2Department of Gastroenterology, Northern Campus of Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201801, China
  • Received:2025-01-16 Published:2026-02-01
  • Corresponding author: Ping Chen
引用本文:

杨满慧, 陈平. 胰腺脂肪浸润与急性胰腺炎相关性的研究进展[J/OL]. 中华消化病与影像杂志(电子版), 2026, 16(01): 91-96.

Manhui Yang, Ping Chen. Research progress on the association between pancreatic fatty infiltration and acute pancreatitis[J/OL]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2026, 16(01): 91-96.

胰腺脂肪浸润又称胰腺脂肪变性,是胰腺内脂质过度堆积的表现,或见于胰腺细胞发生不可逆的脂肪替代,严重时可引起非酒精性脂肪性胰腺病,进一步产生相应的临床表现如胰岛β细胞功能障碍、2型糖尿病、急性胰腺炎等。胰腺脂肪浸润作为多种疾病的启动及危险因素,其诊断与治疗对相关疾病的早期发现及干预密切相关。本文聚焦于胰腺脂肪浸润的流行病学特征及其与急性胰腺炎的关系,强调最新研究进展,并探讨相关病理生理机制,以期为临床诊断和干预提供参考。

Pancreatic fat infiltration, also known as pancreatic steatosis, is characterized by excessive lipid accumulation within the pancreas, which can lead to irreversible fat replacement of pancreatic cells. In severe cases, it can result in non-alcoholic fatty pancreas disease, associated with clinical manifestations such as β-cell dysfunction, type 2 diabetes, and acute pancreatitis. As a trigger and risk factor for various diseases, the diagnosis and management of pancreatic fat infiltration are crucial for early detection and intervention. This review focuses on the epidemiological characteristics of pancreatic fat infiltration and its relationship with acute pancreatitis, highlights the latest research progress, and explores relevant pathophysiological mechanisms, aiming to provide insights for clinical diagnosis and intervention.

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