Abstract:
Objective To investigate the value of differential diagnosis between acinic cell carcinoma and pleomorphic adenoma with contrast-enhanced ultrasound(CEUS).
Methods A total of 20 acinic cell carcinomas and 98 pleomorphic adenomas with presurgical routine two-dimensioned ultrasound and CEUS were retrospectively analyzed in Sichuan Provincial People′s Hospital from April 2008 to May 2016, which were confirmed by surgical pathology.Qontrast 4.0 imaging analysis software was applied to gain peak intensity(PI), time to peak(TTP), regional blood flow(RBF), the max signal intensity(SImax), the mean signal intensity(SImean)through quantitative analysis.
Results The manifestations of conventional two-dimensional ultrasound examination between salivary gland acinic cell carcinoma and pleomorphic adenoma in morphology, internal echo, the boundary showed no statistically significant difference(P>0.05). While CEUS results showed that acinic cell carcinoma was remarkably higher than pleomorphic adenoma in PI(54.28±10.34 vs.44.20±16.41), RBF(68.22±17.86 vs.50.84±26.12), SImax(65.74±9.41 vs.56.54±14.45)and SImean(54.21±10.15 vs.44.26±16.44), and the differences were statistically significant(P<0.05).
Conclusion CEUS quantitative analysis parameters are helpful to differentially diagnose salivary gland acinar cell carcinoma and pleomorphic adenoma.
Key words:
Contrast-enhanced ultrasound,
Salivary gland acinic cell carcinoma,
Salivary gland pleomorphic adenoma,
Differential analysis
Jiamei Gou, Qin Chen. Study on differential diagnosis between acinic cell carcinoma and pleomorphic adenoma with contrast-enhanced ultrasound[J]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2017, 07(06): 247-251.