To evaluated the efficacy of endoscopic multi-point cauterization of rectal mucosa in the treatment of internal rectal prolapse compared with longitudinal folding plus sclerosant injection.

A total of 78 patients with internal rectal prolapse treated in Dongping County People's Hospital from August 2013 to October 2018 were prospectively selected as the research objects. All patients were randomly divided into control group and treatment group, with 40 patients in each group. The control group was treated by longitudinal folding plus sclerosant injection, while the treatment group was treated by multi-point cauterization of rectal mucosa under endoscope. Two patients in the control group were lost to follow-up, and 38 patients were finally included in this study. The constipation symptom scores of the two groups before operation and 3, 6, 12, 18 months after operation were compared.

There was no statistically significant difference in the scores of constipation symptoms between the two groups before and 3 months after operation. The scores of constipation symptoms at 6, 12 and 18 months after operation in the treatment group were all lower than those in the control group (2.0±0.2 vs. 2.2±0.3, 1.5±0.1 vs. 1.9±0.2, 0.7±0.1 vs. 1.7±0.1), and there were statistically significant differences (t=4.773, 11.841, 48.474, all P<0.001).

Endoscopic rectal mucosal multi-point cauterization for the treatment of internal rectal prolapse is easy to operate, the clinical symptoms are significantly improved, and the long-term curative effect is far better than rectal mucosal longitudinal folding plus sclerosant injection.