Effect of enteral nutrition support treatment on lung function and nutritional status of elderly patients with chronic obstructive pulmonary disease at stable stage

doi:10.3877/cma.j.issn.2095-2015.2021.04.005

Abstract

Abstract:

Objective

To analyze the effect of enteral nutrition support treatment on the lung function and nutritional status of elderly patients with chronic obstructive pulmonary disease (COPD) at stable stage.

Methods

A total of 112 elderly patients with stable COPD who received treatment in Xinxing County Hospital of Traditional Chinese Medicine of Guangdong Province from January 2017 to October 2018 were analyzed retrospectively. Among them, 56 patients received conventional treatment (control group), and 56 patients received enteral nutrition support therapy on the basis of the conventional treatment (study group). Nutrition-related indexes and lung function were compared between the two groups before and 3 months after treatment.

Results

Before treatment, there was no statistical significance in the nutritional indexes and lung function indexes between the two groups (all P>0.05). Three months after treatment, the nutritional indexes such as body mass index (BMI), hemoglobin, serum albumin and total protein level in the study group were significantly better than those in the control group, and the lung function indexes such as forced vital capacity (FVC), forced expiratory volume in one second (FEV1), FEV1/FVC and FEV1% were also better than those in the control group, with statistically significant differences (all P<0.05).

Conclusion

Enteral nutrition support in the treatment of elderly COPD patients at stable stage can effectively improve the lung function, improve nutritional status, and effectively control the disease, which is worthy of clinical promotion.

Key words: Enteral nutrition support treatment, Chronic obstructive pulmonary disease, Elderly, Lung function, Nutritional status

Fujian Han. Effect of enteral nutrition support treatment on lung function and nutritional status of elderly patients with chronic obstructive pulmonary disease at stable stage[J]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2021, 11(04): 164-167.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhxhbyyxzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-2015.2021.04.005

https://zhxhbyyxzz.cma-cmc.com.cn/EN/Y2021/V11/I04/164

Figures/Tables 3

References 15

1	苏炜,钱娟,殷锐,等.肠内营养支持对老年慢性阻塞性肺疾病急性加重期并发呼吸衰竭患者血清指标和心肺功能的影响[J].中国临床研究, 2019, 32(12): 1699-1702.
2	Riley CM, Sciurba FC. Diagnosis and Outpatient Management of Chronic Obstructive Pulmonary Disease: A Review [J]. JAMA, 2019, 321(8): 786-797.
3	Segal LN, Martinez FJ. Chronic obstructive pulmonary disease subpopulations and phenotyping [J]. J Allergy Clin Immunol, 2018, 141(6): 1961-1971.
4	Ritchie AI, Wedzicha JA. Definition, Causes, Pathogenesis, and Consequences of Chronic Obstructive Pulmonary Disease Exacerbations [J]. Clin Chest Med, 2020, 41(3): 421-438.
5	Jerng JS, Tang CH, Cheng RW, et al. Healthcare utilization, medical costs and mortality associated with malnutrition in patients with chronic obstructive pulmonary disease: a matched cohort study [J]. Curr Med Res Opin, 2019, 35(7): 1265-1273.
6	杨宗艳,张剑虹,贺晓雪.肠内营养支持和综合护理应用于慢性阻塞性肺疾病患者对营养水平、肺功能和生活质量的影响[J].中国食物与营养, 2019, 25(7): 72-74.
7	李林,刘琴,何兰萍.老年慢性阻塞性肺疾病急性加重期患者发生呼吸机相关性肺炎的危险因素分析[J].中国医刊, 2019, 54(6): 618-621.
8	Labaki WW, Rosenberg SR. Chronic Obstructive Pulmonary Disease [J]. Ann Intern Med, 2020, 173(3): 17-32.
9	Corlateanu A, Mendez Y, Wang Y, et al. "Chronic obstructive pulmonary disease and phenotypes: a state-of-the-art." [J]. Pulmonology, 2020, 26(2): 95-100.
10	Garudadri S, Woodruff PG. Targeting Chronic Obstructive Pulmonary Disease Phenotypes, Endotypes, and Biomarkers [J]. Ann Am Thorac Soc, 2018, 15(4): 234-238.
11	李萍,林桦,张爱丽,等.血清磷水平与老年慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者机械通气撤机结局的相关性分析[J].中华老年医学杂志, 2020, 39(6): 613-617.
12	中华医学会呼吸病学分会介入呼吸病学学组.选择性支气管封堵术治疗难治性气胸专家共识[J].中华结核和呼吸杂志, 2021, 44(5): 417-426.
13	Lareau SC, Fahy B, Meek P, et al. Chronic Obstructive Pulmonary Disease (COPD) [J]. Am J Respir Crit Care Med, 2019, 199(1): 1-2.
14	Scoditti E, Massaro M, Garbarino S, et al. Role of Diet in Chronic Obstructive Pulmonary Disease Prevention and Treatment [J]. Nutrients, 2019, 11(6): 1357.
15	Agustí A, Hogg JC. Update on the Pathogenesis of Chronic Obstructive Pulmonary Disease [J]. N Engl J Med, 2019, 381(13): 1248-1256.

组别	例数	性别（例，男性/女性）	年龄（岁，±s ）	病程（年，±s ）	GOLD分级（例）
组别	例数	性别（例，男性/女性）	年龄（岁，±s ）	病程（年，±s ）	A级	B级	C级
研究组	56	38/18	70.3±2.7	9.2±2.1	15	29	12
对照组	56	36/20	70.1±2.5	9.2±2.3	17	28	11
检验值		χ²=0.159	t=0.410	t=0.072	χ²=0.186
P值		0.690	0.683	0.943	0.911

组别	例数	性别（例，男性/女性）	年龄（岁，±s ）	病程（年，±s ）	GOLD分级（例）
组别	例数	性别（例，男性/女性）	年龄（岁，±s ）	病程（年，±s ）	A级	B级	C级
研究组	56	38/18	70.3±2.7	9.2±2.1	15	29	12
对照组	56	36/20	70.1±2.5	9.2±2.3	17	28	11
检验值		χ²=0.159	t=0.410	t=0.072	χ²=0.186
P值		0.690	0.683	0.943	0.911

组别	例数	BMI（kg/m²）		血红蛋白（g/L）		血清白蛋白（g/L）		总蛋白（g/L）
组别	例数	治疗前	治疗后3个月	治疗前	治疗后3个月	治疗前	治疗后3个月	治疗前	治疗后3个月
研究组	56	20.8±3.5	22.5±2.2	105.6±8.5	114.9±6.2	41.5±6.8	50.4±5.9	58.6±6.9	65.4±5.1
对照组	56	21.1±3.4	21.5±2.5	106.7±8.8	108.2±6.4	42.2±6.7	46.5±5.5	59.2±7.1	61.2±5.4
t值		0.460	2.247	0.673	5.627	0.549	3.618	0.454	4.686
P值		0.646	0.027	0.503	<0.001	0.584	<0.001	0.651	<0.001

组别	例数	BMI（kg/m²）		血红蛋白（g/L）		血清白蛋白（g/L）		总蛋白（g/L）
组别	例数	治疗前	治疗后3个月	治疗前	治疗后3个月	治疗前	治疗后3个月	治疗前	治疗后3个月
研究组	56	20.8±3.5	22.5±2.2	105.6±8.5	114.9±6.2	41.5±6.8	50.4±5.9	58.6±6.9	65.4±5.1
对照组	56	21.1±3.4	21.5±2.5	106.7±8.8	108.2±6.4	42.2±6.7	46.5±5.5	59.2±7.1	61.2±5.4
t值		0.460	2.247	0.673	5.627	0.549	3.618	0.454	4.686
P值		0.646	0.027	0.503	<0.001	0.584	<0.001	0.651	<0.001

组别	例数	FEV（L）		FEV1（L）		FEV1/FVC（%）		FEV1%（%）
组别	例数	入院时	治疗后	入院时	治疗后	入院时	治疗后	入院时	治疗后
观察组	56	2.2±0.4	2.9±0.5	1.7±0.3	2.3±0.4	64.3±5.9	74.7±6.2	61.2±6.5	71.0±4.6
对照组	56	2.2±0.4	2.4±0.5	1.7±0.3	1.9±0.3	65.1±5.7	69.7±6.2	60.5±6.4	66.7±4.4
t值		0.670	4.979	0.347	2.558	0.785	4.264	0.614	4.950
P值		0.504	<0.001	0.729	<0.001	0.434	<0.001	0.541	<0.001

Please choose a citation manager

Content to export