To explore the ultrasonographic manifestations of Castleman disease(CD)in order to improve the understanding of this disease and the accuracy of ultrasound diagnosis.

The ultrasonographic manifestations of 32 patients with CD in Sichuan Provincial People′s Hospital from October 2016 to October 2020 were retrospectively analyzed and compared with clinical classification and pathological diagnosis.The ultrasonographic manifestations were summarized.

Of 32cases of CD, there were 27 cases of localized type(19 cases of transparent vascular type, 7 cases of plasma cell type and 1 case of mixed type), and 5 cases of polycentric type(3 cases of plasma cell type, 1 case of transparent vascular type and 1 case of mixed type). Ultrasound images showed that in CD of transparent vascular type and mixed type dominated by transparent vascular type, most of the lesions were oval shaped, with clear boundaries and inhomogeneous hypoechos, fine dotted line like high enhancement could be seen, with rich internal blood flow signal and blood vessels penetrating the lesion.Contrast-enhanced ultrasound could be seen with high or equal enhancement, peripheral to the center enhancement, and strong echogenic calcification in the interior.In CD of plasma cells type and mixed type mainly based on plasma cells, part of the lesions showed oval shape, clear boundary and inhomogeneous hypoecho, rich internal blood flow signal.Contrast-enhanced ultrasound showed high enhancement or iso-enhancement, peripheral to the center enhancement.

The ultrasound and contrast-enhanced ultrasound images of CD have certain characteristics, which is of great value to the diagnosis and treatment of CD, and can improve the accuracy of clinical diagnosis.