Study of fractional amplitude of low-frequency fluctuation of resting-state fmri in postpartum psychosis

doi:10.3877/cma.j.issn.2095-2015.2022.03.004

Abstract

Abstract:

Objective

To investigate the changes of fractional amplitude of low-frequency fluctuation in patients with postpartum psychosis in resting-state.

Methods

Twelve patients with postpartum psychosis and 14 volunteers matched with age, breast feeding, mode of production, education and primipara(control group)were collected in the 960th Hospital of PLA Joint Logistics Support Force from January 2020 to January 2021.Resting-state functional magnetic resonance imaging(rs-fMRI)data were used to compare fALFF differences in the whole brain of the two groups, and the correlation between fALFF value of postpartum psychosis group with significant differences and the score of the Brief Psychiatric Rating Scales(BPRS)was analyzed.

Results

fALLF values of the parahippocampal gyrus and cingulate gyrus were significantly higher in the postpartum psychosis group than those in the control group(individual voxel P<0.05, voxel value≥55, AlphaSim correction), and there was no correlation with the BPRS score.

Conclusion

Postpartum psychosis can cause aberrant neuronal activity in the limbic system, which is helpful to understand the altered nature of brain neurological function in postpartum psychosis patients.

Key words: Postpartum psychosis, Resting-state functional magnetic resonance imaging, Fractional amplitude of low-frequency fluctuation

Shufen Zhang, Liping Chai, Bo Li, Qinglei Gong, Qinglei Wang, Chunlian Chen. Study of fractional amplitude of low-frequency fluctuation of resting-state fmri in postpartum psychosis[J]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2022, 12(03): 142-145.

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URL: https://zhxhbyyxzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-2015.2022.03.004

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Figures/Tables 3

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组别	例数	年龄(岁)	受教育年限(年)	初产妇	剖宫产	母乳喂养	BPRS评分
PP组	12	31.31±3.42	11.42±3.33	10(83.33%)	7(58.33%)	12(100%)	39.67±2.15
对照组	14	29.63±4.17	11.36±4.13	9(64.29%)	6(42.86%)	14(100%)	18.57±0.94
统计值		0.25^#	0.56^#	1.19^*	1.07^*		33.34^#
P值		0.93	0.65	0.28	0.30		0.00

组别	例数	年龄(岁)	受教育年限(年)	初产妇	剖宫产	母乳喂养	BPRS评分
PP组	12	31.31±3.42	11.42±3.33	10(83.33%)	7(58.33%)	12(100%)	39.67±2.15
对照组	14	29.63±4.17	11.36±4.13	9(64.29%)	6(42.86%)	14(100%)	18.57±0.94
统计值		0.25^#	0.56^#	1.19^*	1.07^*		33.34^#
P值		0.93	0.65	0.28	0.30		0.00

脑区	MNI			体素数(mm³)	t值
脑区	X	Y	Z	体素数(mm³)	t值
海马旁回	-18	-18	-21	63	4.58
扣带回	-18	-39	30	61	4.52

脑区	MNI			体素数(mm³)	t值
脑区	X	Y	Z	体素数(mm³)	t值
海马旁回	-18	-18	-21	63	4.58
扣带回	-18	-39	30	61	4.52

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