To exploring risk factors for perioperative respiratory complications in minimally invasive esophagectomy esophagectomy for esophageal cancer.

A total of 100 patients with squamous esophageal cancer who were underwent total laparoscopic radical esophageal cancer surgery in the Fourth Hospital of Hebei Medical University from January 2021 to October 2022 were retrospectively included as study subjects, and all patients were divided into no-complication group(n=73)and complication group(n=27)according to whether or not they developed respiratory complications during the perioperative period.The baseline and surgery-related data of the patients were pooled and analyzed, and unifactorial and multifactorial logistic regression were applied to analyze the independent risk factors for the occurrence of respiratory complications during the perioperative period of total laparoscopic radical esophageal cancer surgery.

Among the 100 patients with squamous esophageal cancer who were underwent total laparoscopic radical esophageal cancer surgery, 27 patients developed respiratory complications during the perioperative period, including 1 patient with tracheal and bronchial injury, 9 patients with hoarseness accompanied by lung infections, 17 patients with pneumonia.There were no statistically significant differences in gender, body mass index, disease duration, history of alcohol consumption, history of hypertension, tumor location, pathological stage, intraoperative bleeding volume, intraoperative intercostal nerve block, and number of lymph node dissection between the complication group and the non-complication group(P>0.05). There were statistically significant differences in age, smoking history, preoperative diabetes mellitus, preoperative chronic obstructive pulmonary disease(COPD), intraoperative fluid infusion volume, operation time, intraoperative thoracic adhesion, and intraoperative recurrent laryngeal nerve injury between the complication group and the non-complication group(P<0.05). The results of multifactorial logistic regression analysis showed that age≥65 years, history of smoking, preoperative diabetes mellitus, preoperative COPD, intraoperative thoracic adhesions, and intraoperative recurrent laryngeal nerve injury were the independent risk factors for the occurrence of perioperative respiratory complications in total laparoscopic radical surgery for esophageal cancer.

Perioperative respiratory complications during total laparoscopic radical surgery for esophageal cancer are closely related to age≥65 years, smoking history, preoperative diabetes mellitus, preoperative COPD, intraoperative thoracic adhesion, intraoperative recurrent laryngeal nerve injury.We can better prevent the above risk factors, reduce the occurrence of perioperative respiratory complications, and improve the prognosis of patients by performing nebulization, control of blood glucose levels, and neuroprotection during operation.