Abstract:
Objective To observe the clinical efficacy of endoscopic electrocoagulation treatment protocol and endoscopic tissue glue injection treatment protocol in patients with peptic ulcer with bleeding.
Methods The clinical data of 86 patients with upper gastrointestinal bleeding due to peptic ulcer who were admitted to Bozhou People′s Hospital from January 2021 to January 2023 were retrospectively analyzed.According to different treatment programs, all the patients were divided into the control group(which used endoscopic tissue glue injection treatment protocol, n=46)and the observation group(which used endoscopic electrocoagulation treatment protocol, n=40). General baseline data(age, gender, body mass index, disease duration, Forrest classification, type of peptic ulcer, hemoglobin level), clinical efficacy after treatment, intraoperative endoscopic hemostasis rate, rebleeding rate and probability of ectopic embolism within 1 week after operation, indicators related to recovery(time for the disappearance of vomited blood, hospitalization time, time for the conversion of occult blood), and the incidence of adverse reactions were collected and compared between the two groups.
Results There were no statistically significant differences in the general baseline data between the two groups(P>0.05). The total effective rate of treatment in the observation group was higher than that in the control group(P<0.05). The intraoperative endoscopic hemostasis rate of the observation group was significantly higher than that of the control group(P<0.05), and the rebleeding rate in the postoperative period of 1 week was significantly lower than that of the control group(P<0.05), whereas there was no statistically significant difference in ectopic embolism rate in the postoperative period of 1 week between the two groups(P>0.05). The levels of condition recovery-related indicators in the observation group were significantly better than those in the control group(P<0.001). There was no statistically significant difference in the overall incidence of adverse reactions between the two groups(P>0.05).
Conclusion Compared with endoscopic tissue glue injection, endoscopic electrocoagulation has a better hemostatic effect on patients with peptic ulcer with bleeding.It not only reduces the rebleeding rate, but also accelerates the recovery process of the patients.
Key words:
Peptic ulcer bleeding,
Endoscopic tissue glue injection therapy,
Endoscopic electrocoagulation therapy,
Curative effect
Xiankui Gao, Taiyun Zhao, Xingjun Lu, Hongling Zhang, Xiuluo Fang, Bichun Yan, Yin Wang, Yongcui Wang, Miaomiao Liu, Ruonan Ran. Efficacy of endoscopic electrocoagulation and tissue glue injection in the treatment of upper gastrointestinal ulcer with bleeding[J]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2023, 13(06): 452-455.