To investigate the changes of Glasgog-Bradchford score (GBS), post-endoscopic Rockall score (RS), AIMS65 score, lactate/albumin ratio (LAR), monocyte/high-density lipoprotein cholesterol ratio (MHR) and their prognostic value in patients with acute upper gastrointestinal bleeding (AUGIB).

A total of 220 AUGIB patients admitted to Zhangjiagang First People's Hospital from September 2021 to September 2024 were included as study objects, according to the prognosis during hospitalization, the patients were divided into survival group (n=205) and death group (n=15). The GBS, RS and AIMS65 scores, LAR and MHR levels were compared between the two groups, Point-Biserial correlation analysis was used to analyze the correlation between GBS, RS and AIMS65 scores, LAR and MHR and prognosis of AUGIB patients, and the predictive value of GBS, RS and AIMS65 scores, LAR and MHR in AUGIB patients was evaluated by receiver operating characteristic (ROC) curve.

The scores of GBS, RS and AIMS65, LAR and MHR in death group were higher than those in survival group, with statistically significant differences (P<0.05); Pearson correlation analysis showed that GBS, RS and AIMS65 scores, LAR and MHR were positively correlated with prognosis in AUGIB patients (P<0.05); ROC curve analysis results showed that the area under the curve of GBS, RS and AIMS65 scores, LAR and MHR detection were 0.979, 1.000, 0.957, 0.960 and 0.999, respectively, and the sensitivity were 0.930, 0.813, 0.867, 0.821 and 0.902, the specificity was 0.888, 0.995, 0.976, 0.849, 0.980 (P<0.05).

GBS, RS, AIMS65 scores, LAR, and MHR in patients with AUGIB are effective predictors of prognosis, and high scores and elevated markers are associated with poor outcomes and contribute to clinical risk assessment.