To study the effect of adaptive biofeedback training combined with self-designed Chinese prescription in patients with exit obstructive constipation (OOC).

A total of 86 OOC patients admitted to Chengyang District People's Hospital of Qingdao from February 2023 to October 2024 were divided into observation group and control group according to random number table method, with 43 cases in each group. The control group was treated with adaptive biofeedback training, and the observation group was treated with self-designed Chinese prescription on the basis of the control group. The clinical efficacy of two groups of patients after 4 weeks of treatment were compared, the constipation symptom scores before and after treatment, the quality of life questionnaire for constipation patients (PAC-QOL), gastrointestinal hormones (cholecystokinin, motilin, gastrin, vasoactive intestinal peptide), pelvic floor surface electromyography values (average amplitude of rapid contraction, 10 second sustained contraction, and durable contraction), anorectal dynamics (rectal defecation sensation threshold, initial rectal sensation threshold, rectal anal pressure gradient) were compared, and the adverse reactions during treatment were compared.

After 4 weeks of treatment, the total effective rate of observation group was higher than that of control group (P<0.05); the constipation symptom score and PAC-QOL score of the observation group were lower than those of the control group (P<0.05); the levels of cholecystokinin, motilin and gastrin in the observation group were higher than those in the control group (P<0.05), and the level of vasoactive intestinal peptide was lower than that in the control group (P<0.05); the average amplitude of rapid contraction, 10 second sustained contraction and durable contraction in the observation group were higher than those in the control group (P<0.05); the threshold of supportive defecation sensation and initial rectal sensation threshold in the observation group were lower than those in the control group (P<0.05), and the rectal anal pressure gradient was greater than that in the control group (P<0.05). No obvious adverse reactions were observed in both groups.

Adaptive biofeedback training combined with self-designed Chinese prescription has significant effects on OOC patients, which can effectively reduce symptoms, improve quality of life, regulate gastrointestinal hormone secretion, and optimize anorectal dynamics.