Abstract:
Objective To conduct multi-dimensional clinical comprehensive evaluation for Qirong Runchang oral liquid in the treatment of deficiency syndrome constipation by systematic and multidisciplinary methods, to provide reference for clinical rational drug use, clinical promotion of drugs and national medical decision-making.
Methods Based on the Guidelines for the Management of Comprehensive Clinical Evaluation of Pharmaceutical Products (2021) and the Technical Guidelines for Comprehensive Evaluation of Proprietary Chinese Medicines with Multiple Dimensions and Multiple Criteria (2022), using existing statistical data analysis, systematic review, Meta-analysis and cost-effectiveness analysis, clinical comprehensive evaluation was carried out on the treatment of vacuity syndrome constipation from the dimensions of effectiveness, economy, safety, and traditional Chinese medicine characteristics.
Results Qirong Runchang oral liquid had the functions of invigorating Qi and Yin, invigorating spleen and kidney, moistening bowel and laxative, and could improve the total effective rate in the treatment of deficiency syndrome constipation, and has been recommended by many diagnosis and treatment strategies or disease catalogs with good effectiveness. According to the results of cost-effectiveness analysis, the economy of the drug was better. The risk was controllable and the safety was good. According to the results of questionnaire survey, Qirong Runchang oral liquid had better suitability. Traditional Chinese medicine had certain advantages in its characteristics.
Conclusion Qirong Runchang oral liquid has good clinical value. It is suggested to further study the pharmacodynamic mechanism, improve the quality of evidence-based evidence, and give full play to the advantages of clinical value of Qirong Runchang oral liquid.
Key words:
Qirong Runchang oral liquid,
Deficiency syndrome constipation,
System evaluation
Hua Chen, Xinying Zhang, Jie Pan, Pingda Zhou, Qianxi Han, Qian Yang, Wentao Zhu. Comprehensive evaluation of Qirong Runchang oral liquid[J]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2024, 14(03): 263-267.