Emphasizing the application of intestinal gas detection in ulcerative colitis

doi:10.3877/cma.j.issn.2095-2015.2025.04.001

Abstract

Abstract:

Ulcerative colitis (UC) is a chronic relapsing inflammatory bowel disease. Its pathogenesis involves multiple factors including gut microbiota imbalance, immune dysfunction, and metabolic disturbances in the intestine. Intestinal gas detection has recently emerged as a research focus in UC due to its non-invasive nature, potential for dynamic monitoring, and ability to assess disease prognosis. This study systematically examines four key gases: hydrogen (H₂), methane (CH₄), hydrogen sulfide (H₂S), and nitric oxide (NO). We propose that multi-gas ratio models (such as H₂/CH₄ and H₂S/NO) show diagnostic and therapeutic evaluation potential in UC. These models could reduce dependence on endoscopic examinations while providing new strategies for UC diagnosis and treatment management.

Key words: Ulcerative colitis, Intestinal gas detection, Breath test, Non-invasive diagnosis

Yinhao Zhai, Xueliang Jiang. Emphasizing the application of intestinal gas detection in ulcerative colitis[J]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2025, 15(04): 289-293.

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