Relationship between non-alcoholic fatty liver disease and intestinal flora

doi:10.3877/cma.j.issn.2095-2015.2018.04.005

Abstract

Abstract:

Non-alcoholic fatty liver disease(NAFLD)is a clinical pathological syndrome caused by multiple etiologies.It has become one of the most common chronic liver diseases.The complete physiological mechanism of NAFLD is not fully understood.The recent researches suggest that intestinal flora can promote the occurrence and development of NAFLD by regulating the energy metabolism, increasing the endogenous ethanol, adjusting metabolism of bile acid and choline, damaging the immune balance and triggering the low-grade inflammation.This paper summarizes the mechanism of intestinal flora and NAFLD.

Key words: Non-alcoholic fatty liver disease, Intestinal flora, Physiological mechanism, Energy metabolism, Immune balance

Bingxin Wang, Shanshan Bai, Jiajia Zhang, Xiaohong Dang. Relationship between non-alcoholic fatty liver disease and intestinal flora[J]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2018, 08(04): 163-165.

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