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Chinese Journal of Digestion and Medical Imageology(Electronic Edition) ›› 2019, Vol. 09 ›› Issue (05): 193-195. doi: 10.3877/cma.j.issn.2095-2015.2019.05.001

Special Issue:

• Editorial •     Next Articles

Benefits and risks of drug combination therapy for inflammatory bowel disease

Zhi Li1, Wensong Ge2,()   

  1. 1. School Infirmary, Baotu Spring Campus, Shandong University, Jinan 250012, China
    2. Department of Gastroenterology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, China
  • Received:2019-08-06 Online:2019-10-01 Published:2019-10-01
  • Contact: Wensong Ge
  • About author:
    Corresponding author: Ge Wensong, Eamil:

Abstract:

At present, the pathogenesis of inflammatory bowel disease (IBD) is not completely clear. Although more and more biological agents are available, there are still difficulties in the treatment of IBD. In clinical practice, when conventional treatment is not effective, combining several drugs to treat IBD may be an important treatment strategy.But the combination of drugs may increase the risk of infection and tumor while improving the efficacy. Therefore, the application of combined therapy should be selected skillfully combined with the patient′s disease type, disease degree, lesion range, high risk factors and previous medication.

Key words: Inflammatory bowel disease, Ulcerative colitis, Crohn disease, Combination therapy

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