Abstract:
Objective To explore the clinicopathological and CT features of inflammatory myofibroblastic tumor (IMT) of digestive system and peritoneal cavity in order to improve the understanding of the disease.
Methods The clinical, pathological and CT imaging data of 14 patients with IMT confirmed by histopathology in the First Affiliated Hospital of Zhengzhou University from February 2012 to February 2021 were retrospectively collected and analyzed. The location, shape, growth pattern, longest diameter, edge, density, integrity of capsule, ulcer on the surface, enhancement mode and enhancement degree of the lesions were observed and evaluated. Combined with literature analysis, the CT features of the disease were summarized and compared with the pathological results.
Results IMT was located in mesentery in 3 cases, antrum in 2 cases, colon in 2 cases, body of stomach, ileum, ileocecal part, retroperitoneum, gallbladder, liver and pancreas in 1 case. The longest diameter of the lesion was 2-9 (4.90±2.20) cm, 6 cases were irregular and lobulated, 7 cases were single round, 1 case was multiple round. There were complete capsule in 9 cases and incomplete capsule in 5 cases. Tortuous vessels were found in 8 cases and blood supply vessels were found around the tumor in 11 cases. Necrosis and cystic degeneration were found in 12 cases, calcification in 3 cases, fat in 2 cases and hemorrhage in 1 case. After contrast-enhanced, 13 cases showed uneven enhancement, 7 cases showed whole tumor filling enhancement, 6 cases showed edge ring enhancement, and 1 case showed central septal enhancement. Nine cases showed obvious enhancement, 4 cases showed mild enhancement and 1 case showed moderate enhancement.
Conclusion IMT can come from various regions of digestive tract and peritoneal cavity, and its clinical manifestations are not typical. CT images have certain characteristics, which has certain value in the diagnosis of IMT. It can assist in the clinical planning of operation and follow-up after treatment, but the diagnosis depends on pathological and immunohistochemical examination.
Key words:
Inflammatory myofibroblastic tumor,
Digestive system,
Peritoneal cavity,
Tomography, X-ray computed
Wenpeng Huang, Liming Li, Tong Xue, Xiaonan Liu, Shangwen Geng, Chenchen Liu, Jianbo Gao. CT findings and comparison with pathology of inflammatory myofibroblastic tumor of digestive system and peritoneal cavity[J]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2022, 12(03): 133-137.