Application value of dual-source dual-energy computed tomography in 2019 novel coronavirus pneumonia

doi:10.3877/cma.j.issn.2095-2015.2022.04.002

Abstract

Abstract:

Objective

To investigate the effects of dual-source dual-energy computed tomography (CT) scanning with different single-energy reconstructions on the display of interstitial lesions of 2019 novel coronavirus pneumonia (COVID-19), image quality and radiation dose.

Methods

The chest plain scan imaging data of 20 patients with COVID-19 from January to March 2020 in the First Affiliated Hospital of Zhengzhou University were retrospectively analyzed. The radiation dose of dual-source dual-energy CT and conventional CT were compared in the same patient, and the single energy images of 40 keV, 60 keV, 80 keV, 100 keV and 120 keV of dual-source dual-energy CT were compared. The CT value and standard deviation (SD) of interstitial lesions with different energy were compared, and signal-noise ratio (SNR) and contrast-noise ratio (CNR) were calculated. The image quality was assessed by two experienced pulmonary diagnostician using the 5-point method, and the differences in image quality among different single-energy groups were compared.

Results

CT dose index (CTDI_vol) in the dual-source dual-energy CT group was (6.0±2.4) mGy, which decreased by 33% compared with the conventional CT group (8.9±2.9) mGy, with a statistically significant difference (t=10.694, P<0.001). dose length product (DLP) and effective dose (ED) in the dual-source dual-energy CT group were (217.5±79.6) mGy·cm and (3.1±1.1) mSv respectively, which were significantly lower than those in the conventional CT group (333.8±109.0) mGy·cm (t=10.727, P<0.001) and (4.7±1.5) mSv (t=10.730, P<0.001). In the reconstructed images of the 5 groups, with the increase of X-ray energy, the SNR and CNR of the single energy group gradually increased, while the CT value and SD value of the images gradually decreased, and there were statistically significant differences between the two adjacent groups (P<0.001). The consistency of the subjective evaluation of the image quality of the two diagnostic physicians was good (Kappa value was between 0.700 and 0.857, P<0.001). There were statistically significant differences in subjective scores of different energy images (P<0.001), and the subjective score of image in the 80 keV group was the highest.

Conclusions

Compared with the conventional CT, the use of dual-source dual-energy CT reduces the radiation dose. The quality score of 120 keV single-energy image is higher, but the 80 keV single-energy image is more conducive to displaying interstitial lesions, which is of great significance for indicating the progression of disease.

Key words: 2019 novel coronavirus pneumonia, Tomography, X-ray computed, Radiation dose, Image quality

Wenpeng Huang, Jie Liu, Liming Li, Jiameng Hou, Jianbo Gao. Application value of dual-source dual-energy computed tomography in 2019 novel coronavirus pneumonia[J]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2022, 12(04): 198-203.

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References 19

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X线能量	CT值（Hu）	SD值（Hu）	SNR	CNR
40 keV	-305.8±58.7	158.0±33.7	2.0±0.5	0.9±0.5
60 keV	-323.2±60.5	131.4±29.1	2.6±0.7	2.6±0.9
80 keV	-338.0±64.5	113.0±26.8	3.1±0.8	4.3±1.5
100 keV	-344.5±67.1	105.1±25.8	3.4±0.9	5.5±1.9
120 keV	-347.8±68.6	101.2±25.1	3.6±1.0	6.3±2.3
χ²值	52.057	98.543	99.457	98.971
P值	<0.001	<0.001	<0.001	<0.001

X线能量	CT值（Hu）	SD值（Hu）	SNR	CNR
40 keV	-305.8±58.7	158.0±33.7	2.0±0.5	0.9±0.5
60 keV	-323.2±60.5	131.4±29.1	2.6±0.7	2.6±0.9
80 keV	-338.0±64.5	113.0±26.8	3.1±0.8	4.3±1.5
100 keV	-344.5±67.1	105.1±25.8	3.4±0.9	5.5±1.9
120 keV	-347.8±68.6	101.2±25.1	3.6±1.0	6.3±2.3
χ²值	52.057	98.543	99.457	98.971
P值	<0.001	<0.001	<0.001	<0.001

X线能量	医师1	医师2	Kappa值	P值
40 keV	3.2±0.4	3.3±0.4	0.857	<0.001
60 keV	3.9±0.7	3.8±0.8	0.844	<0.001
80 keV	4.8±0.4	4.8±0.6	0.848	<0.001
100 keV	4.5±0.8	4.4±0.8	0.726	<0.001
120 keV	4.2±0.8	4.2±0.8	0.700	<0.001
χ²值	71.538	67.295
P值	<0.001	<0.001

X线能量	医师1	医师2	Kappa值	P值
40 keV	3.2±0.4	3.3±0.4	0.857	<0.001
60 keV	3.9±0.7	3.8±0.8	0.844	<0.001
80 keV	4.8±0.4	4.8±0.6	0.848	<0.001
100 keV	4.5±0.8	4.4±0.8	0.726	<0.001
120 keV	4.2±0.8	4.2±0.8	0.700	<0.001
χ²值	71.538	67.295
P值	<0.001	<0.001

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