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Chinese Journal of Digestion and Medical Imageology(Electronic Edition) ›› 2023, Vol. 13 ›› Issue (01): 46-49. doi: 10.3877/cma.j.issn.2095-2015.2023.01.009

• Review • Previous Articles     Next Articles

Research progress on exosomal long non-coding RNAs in gastric cancer

Huifeng Zhang1, Peng Zhang2, Xiaowei Zhu1, Hong Yu1,()   

  1. 1. Department of Pathology, Taizhou People′s Hospital, Taizhou 225300, China
    2. Department of Thoracic Surgery, Taizhou People′s Hospital, Taizhou 225300, China
  • Received:2022-11-09 Online:2023-02-01 Published:2023-03-10
  • Contact: Hong Yu

Abstract:

Exosomes are stable nanoscale vesicles that widely exist in human body fluids.Exosomes have become a research hot topic in recent years because of their special structure, which enables them to mediate a new mode of intercellular communication and participate in the occurrence and development of tumors.Recent studies have shown that exosomal LncRNAs can not only be used as novel biomarkers for the diagnosis of gastric cancer, but also participate in the proliferation and apoptosis of gastric cancer cells, changes in tumor microenvironment and chemotherapy tolerance.Therefore, this review on the above aspects of exosomal LncRNAs in gastric cancer in recent years is expected to provide references and new ideas for further research.

Key words: Exosomes, Long non-coding RNA, Gastric cancer, Biomarkers, Tumor microenvironment

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