To compare the efficacy of oral solution of magnesium sodium potassium sulfate and polyethylene glycol electrolyte powder on intestinal cleansing during colonoscopy.

A total of 200 patients in Bozhou People′s Hospital requiring colonoscopy from January 1, 2022 to January 1, 2023 were selected.According to random number table method, all patients were randomly divided into observation group(oral solution of magnesium sodium potassium sulfate)and control group(polyethylene glycol electrolyte powder). The success rate of intestinal preparation, the Boston bowel preparation scale(BBPS)of the whole colon and all parts of the intestine, patient satisfaction, the proportion of patients willing to re-use this drug and the safety of the two groups were analyzed respectively.

The BBPS scores of the whole colon and each segment of colon in the observation group and the control group showed 7.8±1.4 vs.7.4±1.3 in the whole colon, 2.6±0.5 vs.2.3±0.5 in the right colon, 2.7±0.5 vs.2.5±0.6 in the transverse colon, 2.7±0.5 vs.2.3±0.6 in the left colon, with statistically significant differences(P<0.05).98% of the observation group and 91% of the control group had intestinal preparation score≥6(P<0.05). The incidence of adverse reactions in the observation group was lower than that in the control group, and the patients in the observation group who were willing to choose the intestinal cleanser again were more than the control group(P<0.05).

The oral solution of magnesium sodium potassium sulfate is better than polyethylene glycol electrolyte powder in the effects of intestinal preparation, which is easy to be accepted by patients.