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Chinese Journal of Digestion and Medical Imageology(Electronic Edition) ›› 2023, Vol. 13 ›› Issue (06): 489-493. doi: 10.3877/cma.j.issn.2095-2015.2023.06.026

• Original Article • Previous Articles     Next Articles

Application of individualized parenteral nutrition in patients with intestinal resection and intestinal dysfunction

Guoying Gu, Yingchun Huang(), Jia Liu, Jianming Ju, Guofeng Yu, Rong Jiang   

  1. Department of General Surgery, Suzhou Integrated Traditional Chinese and Western Medicine Hospital, Suzhou 215101, China
    First Department of Outpatient, Eastern Theater Command General Hospital, Nanjing 210002, China
    Department of Pharmacy, Suzhou Integrated Traditional Chinese and Western Medicine Hospital, Suzhou 215101, China
  • Received:2023-06-18 Online:2023-12-01 Published:2023-12-30
  • Contact: Yingchun Huang

Abstract:

Objective

To explore the application effect of personalized parenteral nutrition in patients with intestinal resection and intestinal dysfunction.

Methods

A single center prospective randomized controlled trial was used, 80 cases of intestinal resection with intestinal dysfunction diagnosed and treated in Suzhou Integrated Traditional Chinese and Western Medicine Hospital from January 2020 to December 2022 were included as the study subjects.They were randomly divided into observation group(40 cases)and control group(40 cases)according to the random number table method.The control group received routine clinical nutrition intervention, while the observation group received individualized parenteral nutrition intervention.The recovery indicators of intestinal function, nutritional indicators, postoperative complications, and hospitalization days between the two groups after intervention were compared.

Results

The observation group showed significantly earlier recovery time of bowel sounds, first exhaust time, and first defecation time than the control group, with statistically significant differences(P<0.05). There were no statistically significant differences between the two groups in body mass index, grip strength, upper arm muscle circumference and triceps skinfold thickness at different time points(P>0.05). The observation group showed significantly better levels of serum albumin, prealbumin, and hemoglobin compared to the control group at 3 and 7 days after surgery, with statistically significant differences(P<0.05). However, there was no statistically significant difference between the two groups at other time points(P>0.05). There was no statistically significant difference between the two groups in terms of postoperative anastomotic leakage, abdominal distension, nausea and vomiting, infection, and total number of complications(P>0.05). The hospitalization days in the observation group were significantly shorter than those in the control group, with a statistically significant difference(P<0.05).

Conclusion

The application of personalized parenteral nutrition in patients with intestinal resection and intestinal dysfunction can promote intestinal function recovery, improve early postoperative laboratory examination indicators, and shorten hospital stay.

Key words: Parenteral nutrition, Individual treatment, Enterectomy, Intestinal dysfunction

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