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Chinese Journal of Digestion and Medical Imageology(Electronic Edition) ›› 2024, Vol. 14 ›› Issue (05): 437-441. doi: 10.3877/cma.j.issn.2095-2015.2024.05.011

• Original Article • Previous Articles    

Effect of dredging fu-organs and purging turbidity therapy combined with somatostatin on prognosis quality of patients with acute biliary pancreatitis treated by endoscopic retrograde cholangiopancreatography

Qian Shang1, Jing Luo1, Zhenshan Zhuo1, Yuanyuan Miao1, Jing Wu1, Zhenlin Liao1,()   

  1. 1. Department of Gastroenterology, The First Hospital of Baoding City, Baoding 071000, China
  • Received:2024-01-16 Online:2024-10-01 Published:2024-09-24
  • Contact: Zhenlin Liao

Abstract:

Objective

To analyze the effect of dredging fu-organs and purging turbidity combined with somatostatin on the prognosis quality of patients with acute biliary pancreatitis (ABP) treated by endoscopic retrograde cholangiopancreatography (ERCP).

Methods

A total of 120 patients with ABP admitted to the First Hospital of Baoding City from April 2019 to July 2020 were randomly divided into the combined group (n=60) and the control group (n=60). Both groups were treated with ERCP, and somatostatin was injected intravenously after operation, while the combined group was treated with the method of dredging fu-organs and purging turbidity. The recovery time of symptoms was compared between the two groups, and the changes of serum amylase, inflammatory index and liver function before and after operation were compared, and the clinical efficacy and complication rate of the two groups were evaluated.

Results

The time to relieve abdominal pain, abdominal distension and blood amylase in the combined group were shorter than those in the control group (P<0.05). The serum amylase in the combined group was lower than that in the control group at 12 h, 24 h and 3 d after operation (P<0.05). The WBC, PCT and CRP in the combined group were lower than those in the control group at 3 days after operation (P<0.05). ALT, AST, GGT and DBIL in the combined group were lower than those in the control group on the 3rd day after operation (P<0.05). The clinical cure rate of the combined group was higher than that of the control group (58.33% vs. 36.67%, P<0.05). The postoperative complications in the combined group were lower than those in the control group (5.00% vs. 16.67%, P<0.05).

Conclusion

For ABP patients, adding the therapy of dredging fu-organs and purging turbidity on the basis of somatostatin after ERCP can shorten the recovery time of symptoms, reduce inflammatory reaction and improve liver function, which is helpful to improve clinical efficacy and reduce the incidence of complications.

Key words: Acute biliary pancreatitis, Dredging fu-organs and purging turbidity, Somatostatin, Endoscopic retrograde cholangiopancreatography

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