To analyze the evaluation of nutritional risk index (NRI), nutritional control status score (CONUT) and urea-creatinine ratio (UCR) on nutritional status and prognosis quality of gastric cancer patients.

A total of 197 patients with gastric cancer admitted to Xuzhou First People’s Hospital from January 2021 to January 2023 were selected and retrospectively analyzed, and their nutritional status were evaluated by the Nutrition Risk Screening Scale 2002 (NRS 2002). Those with NRS 2002 scores of ≥3 and <3 were respectively included in the nutrition risk group and the non-nutrition risk group. The differences of NRI, CONUT and UCR between the two groups were compared, and the correlations between NRI, CONUT, UCR and blood albumin (ALB), prealbumin (PA), hemoglobin (Hb), etc. were calculated using Pearson correlation analysis. According to the patients' prognosis after one-year follow-up, the patients were divided into the good prognosis group and the poor prognosis group, and the baseline data, nutritional status and UCR of the two groups were compared. Logistic multivariate regression model was used to summarize the related factors affecting the prognosis of the patients.

Among the 197 patients, 71 patients had NRS 2002 score ≥3. The NRI score, ALB, PA and Hb in the nutritional risk group were lower than those in the non-nutritional risk group, and their CONUT score and UCR were higher than those in the non-nutritional risk group (P<0.05). Pearson correlation analysis showed that NRS 2002 score, CONUT score and UCR were negatively correlated with ALB, PA and Hb, while NRI score was positively correlated with ALB, PA and Hb (P<0.05). All 197 patients were effectively followed up for 12 to 42 months, with a median follow-up time of 31 months. During the follow-up period, 37 patients had poor prognosis. Logistic regression analysis showed that body mass index<18.5 kg/m², TNM stage Ⅲ, NRS 2002 score ≥3, CONUT score ≥3 and UCR≥20 were all independent risk factors for poor prognosis of patients with gastric cancer, and NRI score ≥99 was a protective factor (P<0.05).

NRI, CONUT and UCR can guide the evaluation of nutritional status of patients with gastric cancer, and the above parameters combined with body mass index and TNM staging are expected to provide new ideas for predicting the prognosis quality of patients with gastric cancer.