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Chinese Journal of Digestion and Medical Imageology(Electronic Edition) ›› 2026, Vol. 16 ›› Issue (01): 91-96. doi: 10.3877/cma.j.issn.2095-2015.2026.01.016

• Review • Previous Articles    

Research progress on the association between pancreatic fatty infiltration and acute pancreatitis

Manhui Yang1, Ping Chen2,()   

  1. 1Department of Gastroenterology, Ruijin Hospital Taicang Branch, Shanghai Jiao Tong University School of Medicine, Taicang Loujiang New City Hospital, Suzhou 215400, China
    2Department of Gastroenterology, Northern Campus of Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201801, China
  • Received:2025-01-16 Online:2026-02-01 Published:2026-02-12
  • Contact: Ping Chen

Abstract:

Pancreatic fat infiltration, also known as pancreatic steatosis, is characterized by excessive lipid accumulation within the pancreas, which can lead to irreversible fat replacement of pancreatic cells. In severe cases, it can result in non-alcoholic fatty pancreas disease, associated with clinical manifestations such as β-cell dysfunction, type 2 diabetes, and acute pancreatitis. As a trigger and risk factor for various diseases, the diagnosis and management of pancreatic fat infiltration are crucial for early detection and intervention. This review focuses on the epidemiological characteristics of pancreatic fat infiltration and its relationship with acute pancreatitis, highlights the latest research progress, and explores relevant pathophysiological mechanisms, aiming to provide insights for clinical diagnosis and intervention.

Key words: Acute pancreatitis, Pancreatic fat infiltration, Risk factor

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