Research progress on diagnosis and treatment of achalasia

doi:10.3877/cma.j.issn.2095-2015.2021.02.006

Abstract

Abstract:

Achalasia (AC) is a primary esophageal motility disorder characterized by impaired relaxation of the lower esophageal sphincter and absent or decreased peristalsis of the esophageal which annual incidence is about 1/100 000-3/100 000. The most common clinical manifestation of AC is dysphagia. At present, the esophageal manometry has become the gold standard for the diagnosis of AC. In addition, diagnostic methods of AC include endoscopy and X-ray barium meal. The pathogenesis of achalasia is not fully clarified, treatment modalities include pharmacological therapy, botulinum toxin injection, balloon dilatation, esophageal stents therapy, laparoscopic Heller myotomy, and per-oral endoscopic myotomy.

Key words: Achalasia, Diagnosis, Treatment

Feifan Lu, Changda Li, Yongjun Shi. Research progress on diagnosis and treatment of achalasia[J]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2021, 11(02): 72-77.

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