To investigate the relationship between hepatic hemodynamics and portal pressure gradient (PPG) by color Doppler ultrasound (CDUS) in cirrhotic patients with portal hypertension (PHT).

A retrospective analysis was conducted on 118 patients with liver cirrhosis complicated with PHT admitted to Shaanxi Kangfu Hospital from January 2022 to December 2024 as the study group, and 100 patients with liver cirrhosis without PHT were selected as the control group in our hospital during the same period. CDUS detection indexes [portal vein main diameter (PVD), portal vein blood velocity (PVV), portal vein blood flow (PVF), splenic vein main diameter (SVD), splenic vein blood velocity (SVV), splenic vein blood flow (SVQ) and PPG level] were compared between the two groups, and the correlation between liver hemodynamics and PPG in cirrhotic portal PHT patients was analyzed by Pearson correlation analysis.

The levels of PVD, SVD and SVQ in the study group were significantly higher than those in the control group, and the levels of PVV, PVF and SVV were significantly lower than those in the control group (P<0.05). The levels of portal vein pressure and PPG in the study group were significantly higher than those in the control group (P<0.05), but there was no significant difference in the level of inferior vena cava pressure between the two groups (P>0.05). The results of Pearson correlation analysis showed that PVD, SVD, SVQ were positively correlated with PPG, while PVV, PVF, SVV were negatively correlated with PPG (P<0.05).

There is a close correlation between liver hemodynamics and PPG in cirrhotic patients with PHT, which can provide reference for clinical diagnosis and treatment.