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中华消化病与影像杂志(电子版) ›› 2019, Vol. 09 ›› Issue (05) : 199 -202. doi: 10.3877/cma.j.issn.2095-2015.2019.05.003

所属专题: 文献

卫生健康事业发展70年巡礼

炎症性肠病治疗目标的演变
葛文松1,()   
  1. 1. 200092 上海交通大学医学院附属新华医院消化内科
  • 收稿日期:2019-08-19 出版日期:2019-10-01
  • 通信作者: 葛文松

Evolution of therapeutic targets for inflammatory bowel disease

Wensong Ge1,()   

  1. 1. Department of Gastroenterology, XinHua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, China
  • Received:2019-08-19 Published:2019-10-01
  • Corresponding author: Wensong Ge
  • About author:
    Corresponding author: Ge Wensong, Email:
引用本文:

葛文松. 炎症性肠病治疗目标的演变[J/OL]. 中华消化病与影像杂志(电子版), 2019, 09(05): 199-202.

Wensong Ge. Evolution of therapeutic targets for inflammatory bowel disease[J/OL]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2019, 09(05): 199-202.

炎症性肠病(IBD)目前发病机制未明,可能与环境、遗传、感染、免疫等多种因素有关。IBD的治疗目标最初为临床缓解,随着基础研究进展及新型生物制剂的临床广泛实践,推荐黏膜愈合作为炎症性肠病的重要治疗目标,最近深度缓解作为一个新的治疗目标被提出,在国外已被广泛接受并应用于疾病评估,本文主要介绍炎症性肠病治疗目标的演变及黏膜愈合、深度缓解作为IBD治疗目标的重要意义。

The pathogenesis of inflammatory bowel disease(IBD)is not clear at present, and it may be related to environment, heredity, infection, immunity and other factors.The initial target for IBD is clinical remission.In recent years, with the development of basic research and extensive clinical practice of new biological agents, mucosal healing is recommended as an important therapeutic target of IBD.Recently, as a new therapeutic target, deep remission has been widely accepted in foreign countries and applied in evaluation of disease efficacy.This review mainly introduces the evolution of therapeutic targets for IBD and the significance of mucosal healing and deep remission as therapeutic targets of IBD.

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