To investigate the value of thin slice CT imaging in the diagnosis of pulmonary ground glass nodules (GGN).

A total of 76 patients with GGN detected by 64-slice spiral CT examination and confirmed by pathology in Huailai Hospital of Traditional Chinese Medicine from January 2018 to July 2021 were retrospectively analyzed. There were 32 cases of benign GGN and 44 cases of malignant GGN. All patients received 5 mm slice thickness conventional spiral CT scan and 1 mm thin slice spiral CT target imaging reconstruction. The imaging and morphological characteristics of benign and malignant GGN were compared, as well as the display effect of different slice thickness of 64-slice spiral CT.

There were statistically significant differences between benign and malignant GGN in lobulation sign, vacuole sign, pleural depression sign, burr sign and unclear margin (P<0.05). There were statistically significant differences between benign and malignant GGN in irregular shape, round or oval shape, patchy shape and polynodular fusion (P<0.05). Conventional spiral CT scan with 5 mm slice thickness and target imaging reconstruction with 1 mm slice spiral CT had statistically significant differences in the detection rates of GGN lobulation sign, vacuole sign, pleural depression sign, unclear edge and burr sign (P<0.05). The imaging features of 1 mm thin-slice target imaging were significantly better than conventional CT scanning with 5 mm slice thickness.

The application of 64-slice spiral CT thin-layer target imaging technology has high clinical application value in the differential diagnosis of benign and malignant GGN, and can significantly improve the detection rate of early lung cancer, providing reference for clinical diagnosis and treatment.