Diagnosis and therapy of rectal neuroendocrine neoplasm

doi:10.3877/cma.j.issn.2095-2015.2018.05.005

Abstract

Abstract:

Objective

To investigate the clinical manifestations, features of endoscopy, pathology and endoscopic treatment of rectal neuroendocrine neoplasm(RNEN).

Methods

The clinical data of 22 patients with RNEN diagnosed by clinic and pathology were retrospectively analyzed.

Results

All patients underwent colonoscopy, and all the surface of RNEN were smooth.A total of 16 patients underwent endoscopic ultrasonography(EUS). Among them, 1 case could not be detected, and the remaining 15 cases originated from submucosa, and 14 cases were manifested as lesions with low level echoes.All the RNEN were removed by endoscopic therapy, including removing by biopsy for 1 case, electroresction for 1 case, endoscopic submucosal dissection(ESD)for 12 cases, endoscopic mucosal resection(EMR)for 3 cases and surgical operation for 1 case.All the cases of specimen were pathologically confirmed, and 21 cases were underwent immunohistochemical examination.Eleven cases were classified as grade G1, 10 cases as grade G2, and 0 case as grade G3.

Conclusion

The colonoscopy and EUS are very important to diagnose RNEN.The efficacy and safety of endoscopic therapy have been verified, which include EMR and ESD.

Key words: Colonoscopy, Endoscopic ultrasonography, Rectal neuroendocrine neoplasm, Endoscopic therapy

Ronggui Zhang, Xiuli Zhang, Qiyang Huang. Diagnosis and therapy of rectal neuroendocrine neoplasm[J]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2018, 08(05): 210-212.

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