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Chinese Journal of Digestion and Medical Imageology(Electronic Edition) ›› 2019, Vol. 09 ›› Issue (01): 37-39. doi: 10.3877/cma.j.issn.2095-2015.2019.01.009

Special Issue:

• Review • Previous Articles     Next Articles

Diagnostic value of serum cysteine protease inhibitors in gastrointestinal tumors

Xiu Wang1, Xinli Ma2, Yiguo Wang3,()   

  1. 1. Graduate School of Taishan Medical College, Tai′an 271016, China
    2. Shandong University Qilu Medical College, Jinan 250012, China
    3. Department of Gastroenterology, Qianfoshan Hospital Affiliated to Shandong University, Jinan 250014, China
  • Received:2018-09-10 Online:2019-02-01 Published:2019-02-01
  • Contact: Yiguo Wang
  • About author:
    Corresponding author: Wang Yiguo, Email:

Abstract:

Cysteine protease is a superfamily of proteolytic enzymes.Cysteine protease inhibitors(CSTs)inhibit protease hydrolysis by combining with cysteine protease and participate in physiological processes such as cell response, aging and programmed cell death.CSTs play an important role in many physiological and pathophysiological aspects, including cell survival and proliferation, differentiation, cell signal transduction and immune regulation and so on.This review summarizes the structure, classification, expression characteristics and possible mechanism of CSTs in gastrointestinal tumors.

Key words: Cysteine protease inhibitor, Gastrointestinal tumor, Expression mechanism

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