Study on the effect of endoscopic nylon rope combined with titanium clip in the treatment of acute non-variceal upper gastrointestinal bleeding

doi:10.3877/cma.j.issn.2095-2015.2025.06.003

Abstract

Abstract:

Objective

To analyze the effect of treating acute non-variceal upper gastrointestinal bleeding (ANVUGIB) by endoscopic nylon rope combined with titanium clip.

Methods

The clinical data of 65 patients with ANVUGIB treated in Affiliated Zhangjiagang Hospital of Soochow University from January 2021 to March 2024 were analyzed retrospectively, and they were divided into control group (34 cases) and observation group (31 cases) by different treatment methods. The control group was treated with endoscopic high-frequency electrocoagulation, while the observation group was treated with endoscopic nylon rope combined with titanium clip purse-string sealing ulcer surface. The clinical efficacy, hemoglobin and hematokrit levels before and after treatment, delayed bleeding rate, readmission rate and wound healing rate in the first and second months after operation were compared between the two groups.

Results

The total effective rate in the observation group was higher than that in the control group (P<0.05). Before treatment, there were no differences in the levels of hemoglobin and hematokrit between the two groups (P>0.05). After treatment, the levels of hemoglobin and hematokrit in both groups increased, and the levels in the observation group were higher than those in the control group (P<0.05). The rate of delayed bleeding and readmission in the observation group were lower than those in the control group (P<0.05), and the hospitalization time was shorter than that in the control group (P<0.05). The wound healing rates in the observation group were higher than those in the control group at 1 month and 2 months after operation (P<0.05).

Conclusion

Endoscopic nylon rope combined with titanium clip is effective in the treatment of ANVUGIB, which can improve hemoglobin and hematokrit levels, reduce delayed bleeding, reduce readmission rate, and heal the wound faster after operation.

Key words: Upper gastrointestinal bleeding, Endoscopic prevention and treatment of non-variceal bleeding of the digestive tract, Nylon rope, Titanium clip

Huan Zou, Bin He, Bin Zhao, Xiao Qu. Study on the effect of endoscopic nylon rope combined with titanium clip in the treatment of acute non-variceal upper gastrointestinal bleeding[J]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2025, 15(06): 570-575.

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URL: https://zhxhbyyxzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-2015.2025.06.003

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Figures/Tables 6

References 25

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组别	例数	性别[例(%)]		年龄(岁,±s)	原发病[例(%)]			Forrest分级[例(%)]				溃疡最大面积(cm²,±s)
组别	例数	男	女	年龄(岁,±s)	十二指肠溃疡	胃溃疡	吻合口溃疡	Ⅰa	Ⅰb	Ⅱa	Ⅱb	溃疡最大面积(cm²,±s)
对照组	34	20(58.82)	14(41.18)	46.80±5.79	10(29.41)	18(52.94)	6(17.65)	5(14.70)	10(29.41)	9(26.47)	10(29.41)	3.01±0.21
观察组	31	16(51.61)	15(48.39)	48.11±5.42	14(45.16)	13(41.94)	4(12.90)	7(22.58)	6(19.35)	6(19.35)	12(38.71)	2.95±0.26
χ²/t值		0.341		0.939	1.738			1.981				1.028
P值		0.559		0.351	0.419			0.576				0.308

组别	例数	性别[例(%)]		年龄(岁,±s)	原发病[例(%)]			Forrest分级[例(%)]				溃疡最大面积(cm²,±s)
组别	例数	男	女	年龄(岁,±s)	十二指肠溃疡	胃溃疡	吻合口溃疡	Ⅰa	Ⅰb	Ⅱa	Ⅱb	溃疡最大面积(cm²,±s)
对照组	34	20(58.82)	14(41.18)	46.80±5.79	10(29.41)	18(52.94)	6(17.65)	5(14.70)	10(29.41)	9(26.47)	10(29.41)	3.01±0.21
观察组	31	16(51.61)	15(48.39)	48.11±5.42	14(45.16)	13(41.94)	4(12.90)	7(22.58)	6(19.35)	6(19.35)	12(38.71)	2.95±0.26
χ²/t值		0.341		0.939	1.738			1.981				1.028
P值		0.559		0.351	0.419			0.576				0.308

组别	例数	显效(例)	有效(例)	无效(例)	总有效率(%)
对照组	34	13	16	5	85.29
观察组	31	23	8	0	100.00

组别	例数	显效(例)	有效(例)	无效(例)	总有效率(%)
对照组	34	13	16	5	85.29
观察组	31	23	8	0	100.00

组别	例数	血红蛋白(g/L)		红细胞压积(g/L)
组别	例数	治疗前	治疗后	治疗前	治疗后
对照组	34	84.69±5.60	90.08±4.17^a	35.57±2.86	38.53±2.57^a
观察组	31	86.55±6.52	93.16±5.99^a	36.54±2.34	40.39±3.12^a
t值		1.237	2.423	1.488	2.632
P值		0.221	0.018	0.142	0.011

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